Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activity and free radical DPPH scavenging
説明 | 5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activity and free radical DPPH scavenging |
In vitro | 5-Hydroxyoxindole was less potent MAO-A inhibitor (IC50 56.8 microM) than isatin (31.8 microM) and especially 5-hydroxyisatin (6.5 microM), but it was the only highly selective MAO-A inhibitor among the all compounds studied (IC50 MAO-A:IC50 MAO-B = 0.044) [1]. |
In vivo | In blood plasma, 5-hydroxyoxindole levels were quite stable [2]. The maximal 5-hydroxyoxindole concentration in plasma was: 5.4 nM (5-hydroxyoxindole molecular weight: 149) [2]. |
分子量 | 149.15 |
分子式 | C8H7NO2 |
CAS No. | 3416-18-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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5-Hydroxyoxindole 3416-18-0 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species antioxidant Inhibitor oxidative ,stress DPPH radical inhibit scavenging peroxidation 5 Hydroxyoxindole lipid 5Hydroxyoxindole inhibitor