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天然化合物

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カタログ番号	製品名	別名	ターゲット
T40612	Manganese(salen) chloride	EUK-8	Others
	Manganese(salen) chloride (EUK-8) (EUK-8) is a superoxide dismutase and catalase mimetic. Manganese(salen) chloride (EUK-8) is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates a...		Others
T8794	4-MMPB	15-Lipoxygenase Inhibitor 1	Apoptosis , Others , Lipoxygenase
	15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxyg...		Apoptosis , Others , Lipoxygenase
T17111	Todralazine hydrochloride	Ecarazine hydrochloride	Adrenergic Receptor
	Todralazine hydrochloride (Ecarazine hydrochloride) is a β2AR blocker and has antioxidant and free radical scavenging activities. Todralazine hydrochloride can be used in anti-hypertensive research.		Adrenergic Receptor
T1229	Erdosteine	RV 144,KW-9144	NF-κB , Antibacterial , Adenosine deaminase
	Erdosteine (RV 144) is a homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus production and viscosity, by which facilitating mucocili...		NF-κB , Antibacterial , Adenosine deaminase
T3289	Amifostine	Ethyol,WR2721,Gammaphos	Others , HIF/HIF Prolyl-Hydroxylase
	Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.		Others , HIF/HIF Prolyl-Hydroxylase
T41345	AFMK	Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine	Apoptosis , Free radical scavengers , Antioxidant , Endogenous Metabolite
	AFMK (Formyl-N-acetyl-5-methoxykynurenamine) is an active metabolite of Melatonin with antioxidant and free radical scavenging activity. AFMK is a modulator of apoptosis and improves the anti-tumor effect of Gemcitabine ...
T78554	Tyrosinase-IN-12		Tyrosinase
	Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25 µM. Tyrosinase-IN-12 has significant antioxidant and free r...		Tyrosinase
T9560	MAO-B-IN-2
	MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC 50 values of 0.51 and 7.00 μM, respectively. MAO-B-IN-2 attenuates H2O2-induced cellular damage via good ROS scavenging property.
T63750	α-Amylase-IN-1		Antioxidant , Amylase
	α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM). α-Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging of DPPH free radicals, and can be used in the study of diabetes and oxidat...		Antioxidant , Amylase
T23046	N-tert-butyl-α-Phenylnitrone	(Z)-N-benzylidene-2-Methylpropan-2-aMine oxide	ROS , COX
	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) possesses potent reactive oxyge...		ROS , COX
T77578	CHBO4		MAO , ROS
	CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the Ki value was 0.010 ± 0.005 μM.CHBO4 reduces cellular damag...		MAO , ROS
T12781	RV01		Others
	RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc...		Others
T31834	FMHM
	FMHM is a TRAF6 scavenging agent via ubiquitination-dependent mode.
T23816	BPIC
	BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.
T17112	Todralazine	Ecarazine	Others
	Todralazine is an anti-hypertensive agent and acts as a β2AR blocker. It also has an antioxidant and free radical scavenging activity.		Others
T71322	CV 6504
	CV 6504 is a dual inhibitor of thromboxane A2 synthetase and 5-lipoxygenase. It also possesses oxygen scavenging activity.
T35964	MitoTEMPO hydrate
	MitoTEMPO is a mitochondria-targeted superoxide dismutase mimetic that possesses superoxide and alkyl radical scavenging properties.[1] This compound combines the antioxidant piperidine nitroxide TEMPO with the lipophili...
T76576	Arg-Tyr
	Arg-Tyr, a dipeptide, demonstrates significant activity in scavenging hydroxyl radicals and hydrogen peroxide [1].
T38945	Carboxy-PTIO
	Carboxy-PTIO is a highly effective nitric oxide (NO) scavenger known for its rapid reaction rate with NO, resulting in the formation of nitric dioxide (NO2). Its direct scavenging action against NO plays a crucial role i...
T40979	XJB-5-131
	XJB-5-131 is a synthetic, bi-functional antioxidant specifically designed to target mitochondria for the scavenging of reactive oxygen species (ROS) and electrons, thereby acting as a radical scavenger. Additionally, it ...
T38646	GKT136901 hydrochloride	GKT136901 hydrochloride
	GKT136901 hydrochloride is a powerful, selective, and orally active inhibitor of NADPH oxidase (NOX1/4). It exhibits K i values of 160 nM and 165 nM against NOX1 and NOX4, respectively. Additionally, GKT136901 hydrochlor...
T61579	BuChE-IN-5
	BuChE-IN-5 (compound 25b) is a highly potent BuChE inhibitor, displaying an IC50 value of 1.94 μM. It effectively inhibits aggregation of Aβ and tau protein in Escherichia coli. Furthermore, BuChE-IN-5 exhibits considera...
T35590	Graphislactone A
	Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislact...
T81800	MHLWAAK
	MHLWAAK, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging capabilities. It effectively shields zebrafish larvae against H2O2-induced oxidative ...
T81828	MDYYFEER
	MDYYFEER, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits strong DPPH and ABTS radical scavenging activities. It has been demonstrated to protect zebrafish larvae against oxidative d...
T81799	MHLWAAK TFA
	MHLWAAK TFA, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging properties. It effectively shields zebrafish larvae against oxidative damage ...
T81827	MDYYFEER TFA
	MDYYFEER TFA, an antioxidant peptide derived from pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging capability. This compound effectively shields zebrafish larvae against oxidative...
T81863	MAQAAEYYR TFA
	MAQAAEYYR TFA, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent DPPH and ABTS radical scavenging properties. It confers protection to zebrafish larvae against oxidative dam...
T75501	Morin 3-O-β-D-glucopyranoside
	Morin 3-O-β-D-glucopyranoside, a natural flavonoid, exhibits antifungal, anticancer, and antioxidant properties. This compound also inhibits reverse transcriptase, protein-tyrosine kinase, and xanthine oxidase, while dem...
T82408	Ferroptosis-IN-3		Ferroptosis
	Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM). It exhibits radical scavenging abilities against DPPH and ABTS...		Ferroptosis
T81864	MAQAAEYYR
	MAQAAEYYR, an antioxidant peptide derived from the pancreatin hydrolysate of C-phycocyanin, exhibits potent scavenging activities against DPPH and ABTS radicals. It also confers protection to zebrafish larvae against oxi...
T79603	3,7-DMF		TGF-beta/Smad
	3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation. By inducing antioxidant gene expression and scavenging reactive ox...		TGF-beta/Smad
T78067	Stobadine	(-)-Stobadine	Reactive Oxygen Species
	Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes. It shows promise in the development of cardio- and neuroprotective agents owing to its mechan...		Reactive Oxygen Species
T78817	AChE-IN-39
	AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to ameliorate cognitive impairments in an aluminum chloride (AlCl...
T83357	3-Hydroxy-2-(palmitoyloxy)propyl stearat
	3-Hydroxy-2-(palmitoyloxy)propyl stearate is a non-volatile compound isolated from the less polar fractions of the brown macroalga Fucus virsoides J. Agardh. It exhibits significant free radical scavenging activity and i...
T35975	6,9-Dichloro-1,2,3,4-tetrahydroacridine
	6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids...
T79260	MCI		Reactive Oxygen Species
	MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation through macrophage reprogramming by enhancing ROS scavenging a...		Reactive Oxygen Species
T61312	Antioxidant agent-3
	Antioxidant agent-3 (Compound 14q), a potent antioxidant, exhibits strong scavenging activity against DPPH radicals and ABTS+ radicals, with IC50 values of 26.58 μM and 30.31 μM, respectively. Additionally, it enhances t...
T76598	H-Ser-Tyr-OH
	H-Ser-Tyr-OH, a dipeptide comprising serine and tyrosine (incorrectly described as consisting of glutamic acid, glycine, and histidine), exhibits a significant capability to form a copper(II) complex with copper ions, en...
T60421	Antitumor agent-68
	Antitumor agent-68 is a potent tubulin inhibitor that exhibits good antitumor activity with IC 50 s of 3.6 and 3.8 μM for cervical cancer cells line HeLa and breast cancer cells line MCF-7 cells, respectively. Antitumor ...
T81396	PRO-F
	PRO-F, a photoactivable hydrogen sulfide (H2S) donor, possesses reactive oxygen species (ROS) scavenging properties and emits a fluorescent signal upon light activation, enabling real-time tracking of H2S release. Its ac...
T78781	TrxR1-IN-1
	Compound 5j, also known as TrxR1-IN-1, is a TrxR1 inhibitor with an IC50 of 8.8 μM. It exhibits anticancer activity, demonstrating IC50 values of 1.5 μM in MCF-7, 1.7 μM in HeLa, 2.4 μM in BGC-823, 2.8 μM in SW-480, and ...
T36499	CuATSM
	The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals. Mutations in SOD1, which alter its metal binding capacity and can result in protein misfolding ...
T60447	α-Amylase-IN-3
	α-Amylase-IN-3 (Compound 4) is a non-competitive inhibitor of α-Amylase with an IC50 value of 18.04 μM. α-Amylase-IN-3 has radical scavenging activities with IC50 values of 16.04 μM for DPPH and 16.99 μM for ABTS, respec...
T72763	AChE/BuChE-IN-1
	AChE/BuChE-IN-1, a selective butyrylcholinesterase (BuChE) inhibitor derived from chrysin, exhibits a potent efficacy with an IC50 of 0.48 μM against BuChE and a lesser inhibitory effect on acetylcholinesterase (AChE) wi...

Compounds

Manganese(salen) chloride

Synonym: 15-Lipoxygenase Inhibitor 1

Target: Apoptosis, Others, Lipoxygenase

Todralazine hydrochloride

T17111

Synonym: Ecarazine hydrochloride

Target: Adrenergic Receptor

Erdosteine

T1229

Synonym: RV 144,KW-9144

Target: NF-κB, Antibacterial, Adenosine deaminase

Amifostine

T3289

Synonym: Ethyol,WR2721,Gammaphos

Target: Others, HIF/HIF Prolyl-Hydroxylase

AFMK

T41345

Synonym: Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine

Target: Apoptosis, Free radical scavengers, Antioxidant, Endogenous Metabolite

Target: Antioxidant, Amylase

N-tert-butyl-α-Phenylnitrone

T23046

Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide

GKT136901 hydrochloride

T38646

Synonym: GKT136901 hydrochloride

Morin 3-O-β-D-glucopyranoside

Target: TGF-beta/Smad

Stobadine

T78067

Synonym: (-)-Stobadine

Target: Reactive Oxygen Species

3-Hydroxy-2-(palmitoyloxy)propyl stearat

T83357

Synonym:

Target:

6,9-Dichloro-1,2,3,4-tetrahydroacridine

Target: Reactive Oxygen Species

カタログ番号	製品名	別名	ターゲット
T9057	Norbergenin		IL Receptor , TNF , Reactive Oxygen Species
	Norbergenin is a chemical compound. It is the O-demethylated derivative of bergenin. It can be isolated from rhizomes of Bergenia stracheyi.		IL Receptor , TNF , Reactive Oxygen Species
T3S0218	Thonningianin A		Apoptosis , Others
	1. Thonningianin A has anti-cancer activities.2. Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor.3. Thonningianin A has antioxidant property, involves radical scavenging, anti-superox...		Apoptosis , Others
T6S1440	Loganic acid	Loganate	Others
	1. Loganic acid (Loganate) and geniposide exhibit both sides effect on superoxide generation.		Others
T9135	Epirosmanol		Others
	Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa).		Others
T2S1181	Aloenin	Aloenin A,Aloearbonaside	Beta-Secretase , AChR
	1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.		Beta-Secretase , AChR
T22308	Dimboa	2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one	Others , Antibacterial , Antibiotic , Antifungal
	Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal compound used in crops.		Others , Antibacterial , Antibiotic , Antifungal
TN6706	3-demethylcolchicine		Reactive Oxygen Species
	3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.		Reactive Oxygen Species
T5728	OsMundacetone	4-(3,4-Dihydroxyphenyl)-3-buten-2-one	Apoptosis , Reactive Oxygen Species
	OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.		Apoptosis , Reactive Oxygen Species
TN2165	Rubrofusarin gentiobioside	Rubrofusarin-6-O-beta-D-gentiobioside	ERK , NF-κB , TGF-beta/Smad
	Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive...		ERK , NF-κB , TGF-beta/Smad
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
TN6909	Polyporusterone B	(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one	Others
	Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic aci...		Others
T4S2084	3'-Methoxypuerarin	3’- Methoxy Puerarin	Antioxidant
	3'-Methoxypuerarin shows neuron protection activity, it can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 3'-Methoxypuerarin(3’- Methoxy Puerarin) has antioxidant activities, it...		Antioxidant
T5S0281	Tubuloside A		NOS
	Tubuloside A ( 8.6 microM) can inhibit D-galactosamine-induced death of hepatocytes. Tubuloside A has NO radical-scavenging activity, which possibly contributes to its anti-inflammatory effects.Tubuloside A shows stronge...		NOS
T2936	Antiarol	3,4,5-trimethoxyphenol	Others
	Antiarol (3,4,5-trimethoxyphenol) is a member of aromatic phenols and exhibits moderate DPPH free radical scavenging activity.		Others
T7781	Reynoutrin	Reinutrin,Quercetin-3-D-xyloside	Reactive Oxygen Species
	Reynoutrin (Reinutrin) with antioxidant and radical-scavenging activity.		Reactive Oxygen Species
T3845	(+)-Gallocatechin	Gallocatechol,D-Gallocatechin	Others
	(+)-Gallocatechin (Gallocatechol) possesses free radical scavenging ability. (+)-Gallocatechin has moderate affinity to the human cannabinoid receptor.		Others
TN1137	Isobutylshikonin		Others
	Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·.		Others
TN1513	Clitorin		PKC , Antifection
	Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.		PKC , Antifection
TN1002	Blumeatin		ROS
	Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.		ROS
T3828	(-)-Gallocatechin	(2S,3R)-gallocatechin,(−)-GC	Others
	(-)-Gallocatechin ((−)-GC) has free radical scavenging ability and moderate affinity to the human cannabinoid receptor.		Others
TN2008	Okanin		NF-κB , TLR
	Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.		NF-κB , TLR
TN1916	Matairesinol		ATPase , p38 MAPK , ROS
	Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α± in hypoxic HeLa cells.		ATPase , p38 MAPK , ROS
T2S1434	Bergaptol	5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-Hydroxypsoralen	P450
	1. Bergaptol (4-Hydroxybergapten) shows very good radical scavenging activity. 2. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme.		P450
TN1490	Chrysoeriol		ERK , p38 MAPK , Akt
	Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect.		ERK , p38 MAPK , Akt
T3905	Isomangiferin		Free radical scavengers , Antiviral , Influenza Virus
	Isomangiferin has an antiviral effect, may due to their capability of inhibiting virus replication within cells. It also has antioxidant and radical-scavenging activities.		Free radical scavengers , Antiviral , Influenza Virus
TN1274	4-Allylcatechol	4-Allylpyrocatechol,Hydroxychavicol	Others
	4-Allylcatechol (Hydroxychavicol) has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical ...		Others
T2S1086	Nepitrin	Nepetin-7-glucoside	Antioxidant
	1. Nepitrin (Nepetin-7-glucoside) has antioxidant activity in human HL6 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation.		Antioxidant
T8087	Tropolone		Tyrosinase
	Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion		Tyrosinase
T6S1930	Schisanhenol	Schizanhenol,Gomisin-K3	Antioxidant
	1. Schisanhenol (Schizanhenol) can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals. 3. Schisanheno...		Antioxidant
TN1816	Kadsurin		Antioxidant
	Kadsurin has anti-oxidant activity, it induces enzymes capable of scavenging oxygen radical species in the liver. Kadsurin may be valuable antitumor promoters or chemopreventors.		Antioxidant
TN6489	Regaloside A		Others
	Regaloside A is a phenylpropane derived from lily of the valley that shows DPPH free radical scavenging activity at 160 ppm.Regaloside A has anti-inflammatory activity and antidepressant activity.		Others
T2759	Loganin	Loganoside	Apoptosis , NF-κB , BACE , AChR , AChE
	Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has displayed potent free-radical-scavenging activity and inhibitor...		Apoptosis , NF-κB , BACE , AChR , AChE
T3383	Cimifugin	Cimitin	Others
	Cimifugin (Cimitin) inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system.		Others
TN1644	Flavanomarein		Others
	Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...		Others
TN2031	γ-Terpinene	Moslene,p-Mentha-1,4-diene,Crithmene	Antioxidant
	γ-Terpinene (p-Mentha-1,4-diene) is a monoterpene compound with high antioxidant properties suitable for oral consumption. It displays direct radical scavenging abilities and is known to be a potent antinociceptive agent...		Antioxidant
TN1788	Isookanin		Amylase
	Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml).		Amylase
T1716	Echinacoside		Reactive Oxygen Species , Wnt/beta-catenin
	Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilat...		Reactive Oxygen Species , Wnt/beta-catenin
T5S0089	Kaempferol-3-O-glucorhamnoside	Kaempferol 3-glucorhamnoside	Antioxidant , p38 MAPK , NF-κB
	Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside), a flavonoid derived from plant Thesium chinense Turcz, inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo[1]. Kaempferol-3-O-gl...		Antioxidant , p38 MAPK , NF-κB
T39887	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid	(S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid	Others
	(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid ((S)-3-(4-Hydroxyphenyl)lactic acid) (compound 1) is a metabolite found in the culture medium of Leuconostoc mesenteroides . (S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid...		Others
TJS2190	Nordihydroguaiaretic acid	NDGA,Dihydronorguaiaretic Acid	Antioxidant , Ferroptosis , Lipoxygenase , Autophagy
	Nordihydroguaiaretic acid (NDGA) (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibito...		Antioxidant , Ferroptosis , Lipoxygenase , Autophagy
T2996	Tetrandrine	NSC-77037,d-Tetrandrine,Hanfangchin A,Fanchinine,Sinomenine A	Potassium Channel , Calcium Channel
	Tetrandrine (Sinomenine A) is a natural, bis-benzylisoquinoline alkaloid isolated from the root of the plant. Tetrandrine non-selectively inhibits calcium channel activity and induces G1 blockade of the G1 phase of the c...		Potassium Channel , Calcium Channel
TN1420	Bacopaside I		Others
	Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ...		Others
TN1601	Effusol		Caspase
	Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampa...		Caspase
TN1742	Homovanillyl alcohol		TNF , Drug Metabolite
	Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homovanillyl alcohol displays high scavenging activities, it pr...		TNF , Drug Metabolite
T0562	Protocatechuic acid	3, 4-Dihydroxybenzoic acid,Protocatechuate,3,4-Dihydroxybenzoic acid	Others
	Protocatechuic acid (3, 4-Dihydroxybenzoic acid) (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protective agent ...		Others
TN3972	Epimedokoreanin B		Apoptosis , Others , Antibacterial
	Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-...		Apoptosis , Others , Antibacterial
TN3469	Aucuparin	2,6-dimethoxy-4-phenylphenol	NADPH-oxidase
	Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by bleomycin (BLM). ABTS and FRAP showed clear scavenging act...		NADPH-oxidase
T2S1635	3-Isomangostin		MTH1
	3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...		MTH1
T7984	2-Hydroxyflavanone		Others
	2-Hydroxyflavanone is a naturally occurring flavonoid found in many plants and fruits. It has antioxidant, anti-inflammatory and anti-tumor activity, scavenging free radicals, reducing inflammation and inhibiting the gro...		Others
T0926	Azelaic acid	Finacea,Azelex,Nonanedioic acid,Anchoic acid	Others , DNA/RNA Synthesis , Endogenous Metabolite
	Azelaic acid (Anchoic acid) is a component of hair and skin conditioners and is produced by the ozonolysis of oleic acid. Azelaic acid has bacteriostatic activity against Propionibacterium acnes and Staphylococcus epider...		Others , DNA/RNA Synthesis , Endogenous Metabolite
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天然物製品

norbergenin

T9057

Synonym:

Target: IL Receptor, TNF, Reactive Oxygen Species

Thonningianin A

T3S0218

Synonym:

Target: Apoptosis, Others

Synonym: Aloenin A,Aloearbonaside

Target: Beta-Secretase, AChR

Dimboa

T22308

Synonym: 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one

Target: Others, Antibacterial, Antibiotic, Antifungal

3-demethylcolchicine

TN6706

Synonym:

Target: Reactive Oxygen Species

OsMundacetone

T5728

Synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one

Target: Apoptosis, Reactive Oxygen Species

Rubrofusarin gentiobioside

TN2165

Synonym: Rubrofusarin-6-O-beta-D-gentiobioside

Target: ERK, NF-κB, TGF-beta/Smad

5-Hydroxyoxindole

T37710

Synonym:

Target: Reactive Oxygen Species

Polyporusterone B

TN6909

Synonym: (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one

Target: Others

3'-Methoxypuerarin

T4S2084

Synonym: 3’- Methoxy Puerarin

Synonym: 3,4,5-trimethoxyphenol

Target: Others

Reynoutrin

T7781

Synonym: Reinutrin,Quercetin-3-D-xyloside

Target: Reactive Oxygen Species

(+)-Gallocatechin

T3845

Synonym: Gallocatechol,D-Gallocatechin

Target: PKC, Antifection

Synonym: (2S,3R)-gallocatechin,(−)-GC

Target: ATPase, p38 MAPK, ROS

Bergaptol

T2S1434

Synonym: 5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-Hydroxypsoralen

Target: ERK, p38 MAPK, Akt

Isomangiferin

T3905

Synonym:

Target: Free radical scavengers, Antiviral, Influenza Virus

4-Allylcatechol

TN1274

Synonym: 4-Allylpyrocatechol,Hydroxychavicol

Target: Others

Nepitrin

T2S1086

Synonym: Nepetin-7-glucoside

Synonym: Schizanhenol,Gomisin-K3

Target: Apoptosis, NF-κB, BACE, AChR, AChE

Synonym: Moslene,p-Mentha-1,4-diene,Crithmene

Target: Reactive Oxygen Species, Wnt/beta-catenin

Kaempferol-3-O-glucorhamnoside

T5S0089

Synonym: Kaempferol 3-glucorhamnoside

Target: Antioxidant, p38 MAPK, NF-κB

(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

T39887

Synonym: (S)-3-(4-Hydroxyphenyl)lactic acid,(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid

Target: Others

Nordihydroguaiaretic acid

TJS2190

Synonym: NDGA,Dihydronorguaiaretic Acid

Target: Antioxidant, Ferroptosis, Lipoxygenase, Autophagy

Tetrandrine

T2996

Synonym: NSC-77037,d-Tetrandrine,Hanfangchin A,Fanchinine,Sinomenine A

Target: Potassium Channel, Calcium Channel

Target: TNF, Drug Metabolite

Protocatechuic acid

T0562

Synonym: 3, 4-Dihydroxybenzoic acid,Protocatechuate,3,4-Dihydroxybenzoic acid

Target: Apoptosis, Others, Antibacterial

Aucuparin

TN3469

Synonym: 2,6-dimethoxy-4-phenylphenol

Target: NADPH-oxidase

Synonym: Finacea,Azelex,Nonanedioic acid,Anchoic acid

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02973	VDB Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombi...
TMPH-02972	VDB Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombi...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPJ-00753	Myoglobin Protein, Human, Recombinant (His)	Human	E. coli
	Myoglobin(MB) is a cytoplasmic protein expressed in myocytes of the heart and skeletal muscle that reversibly binds oxygen. It belongs to the globin family. Functions of myoglobin include oxygen storage and transport, as...
TMPY-01679	LCN1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEG...

VDB Protein, Mouse, Recombinant (His)

TMPH-02973

Species: Mouse

Expression System: P. pastoris (Yeast)

VDB Protein, Mouse, Recombinant (E. coli, His)

TMPH-02972

Species: Mouse

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

Myoglobin Protein, Human, Recombinant (His)

TMPJ-00753

Species: Human

Expression System: E. coli

LCN1 Protein, Human, Recombinant (His)

TMPY-01679

Species: Human

Expression System: HEK293 Cells

カタログ番号	製品名
L6120	Flavonoid Natural Product Library		514 compounds
	A unique collection of 514 flavonoids can be used for high throughput and high content screening；

ライブラリー

Flavonoid Natural Product Library

L6120

Compounds: 514