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カタログ番号 | 製品名 | 別名 | ターゲット |
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T10166 | Lipid peroxidation inhibitor 1 | Others | |
Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM). | |||
T22022 | Adaptaquin | HIF | |
Adaptaquin is an inhibitor of the hypoxia-inducing factor prolyl hydroxylase (HIF-PH) [1] [2]. | |||
T0342 | Carvedilol phosphate hemihydrate | Carvedilol phosphate,BM 14190 (phosphate hemihydrate) | VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy |
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom... | |||
T9956 | VK-28 | Mitochondrial Metabolism , Lipid | |
VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation. | |||
T5523 | Imidazole ketone erastin | IKE | Ferroptosis |
Imidazole ketone erastin (IKE) is an iron death inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and l... | |||
T77288 | KKII5 | Lipoxygenase | |
KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons. | |||
T60084 | FINO2 | Ferroptosis | |
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 i... | |||
T28978 | Tirilazad mesylate | U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate | Antiviral |
Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c... | |||
T63992 | KS100 | ||
KS100 is a potent inhibitor of ALDH, acting on ALDH1A1 (IC50: 334 nM), ALDH2 (IC50: 2137 nM) and ALDH3A1 (IC50: 360 nM). KS100 significantly increases ROS activity, lipid peroxidation and the accumulation of toxic aldehy... | |||
T4313 | Tinoridine hydrochloride | Nonflamin,Y-3642 hydrochloride | COX , Glutathione Peroxidase |
Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid... | |||
T25829 | Mopidamol | RA233,RA 233,RA-233,Rapenton,OLX 102 | PDE |
Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental diabetes. | |||
T35689 | MTP 131 acetate | Others | |
MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging... | |||
T30863 | CH 402 | CH-402,CH402 | |
CH 402 inhibits lipid peroxidation. | |||
T69462 | Deulinoleic acid | ||
Deulinoleic acid is a lipid peroxidation inhibitor and antioxidant. | |||
T70708 | U 92032 | ||
U 92032 is a T-channel antagonist and antioxidant that inhibits lipid peroxidation. | |||
T69867 | BN80933 | ||
BN80933 is a dual inhibitor of lipid peroxidation and neuronal nitric oxide synthase; Neuroprotectant. | |||
T35646 | 4-oxo-2-Nonenal | 4-oxo-2-Nonenal,4-ONE | |
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. [1] [2] It exhibits various biological activities such as cytotoxicity, ... | |||
T24255 | KB 5666 | KB-5666,KB5666 | |
KB 5666, a quinazoline derivative, is a lipid peroxidation inhibitor. It protects the brain from both cellular and functional consequences of ischemia. | |||
T19465 | N6-Etheno 2'-deoxyadenosine | Others | |
N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues. | |||
T35963 | MitoPerOx | ||
MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria. It is composed of a BODIPY fluorophore conjugated via a dienyl link to a triphenylphosphonium cat... | |||
T23853 | Carazostatin | ||
Carazostatin is an antioxidant, free radical scavenger, and potent lipid peroxidation inhibitor. | |||
T28082 | Mollugogenol A | ||
Mollugogenol A is a Gammacerane from Mollugo pentaphylla. It is an antifungal saponin with spermatocidal activity. Mollugogenol A also involves sperm membrane damage by increased lipid peroxidation. | |||
T69427 | Peridinin | ||
Peridinin is an exceptionally potent and membrane-embedded inhibitor of bilayer lipid peroxidation. | |||
T28673 | SB 209995 | SB-209995,SB209995 | |
SB 209995, a potent antioxidant, inhibits oxygen-radical-mediated lipid peroxidation and cytotoxicity. | |||
T70947 | U-78517F | ||
U-78517F is a potent inhibitor of lipid peroxidation. | |||
T35590 | Graphislactone A | ||
Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislact... | |||
T39652 | BODIPY 581/591 C11 | BODIPY 581/591 C11 | |
C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation . C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 i... | |||
T36002 | 4-hydroxy Hexenal | 4-HHE,4-hydroxy Hexenal | |
4-hydroxy Hexenal is a lipid peroxidation product derived from oxidized ω-3 fatty acids such as DHA. [1][2] | |||
T22370 | Mitoquinol mesylate | Others | |
Mitoquinol, a ubiquinone derivative, specifically accumulates in mitochondria due to the covalent attachment of the cation triphenylphosphonium. Mitoquinol is an antioxidant, protecting mitochondria from oxidative damage... | |||
T36509 | U-74389G | U-74389G,Methylated Tirilazad | |
U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4] | |||
T36175 | AAPH | ||
AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces... | |||
T36168 | 8-iso-16-cyclohexyl-tetranor Prostaglandin E2 | 8-iso-16-cyclohexyl-tetranor Prostaglandin E2 | |
8-iso Prostaglandin E2 (8-iso PGE2) is one of several isoprostanes produced from polyunsaturated fatty acids during lipid peroxidation. 8-iso-16-cyclohexyl-tetranor PGE2 is a synthetic analog of 8-iso PGE2. There are no ... | |||
T35462 | (±)11-HETE | ||
(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid . The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPL... | |||
T36169 | 15-LOX-1 inhibitor 1 | ||
9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and I... | |||
T36164 | 8-iso Prostaglandin F3α | 8-iso Prostaglandin F3α,8-epi PGF3α | |
8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of h... | |||
T78548 | 3-Hydroxyxanthone | 3-Hydroxy-xanthen-9-one | Integrin |
3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) and suppresses TNF-alpha-induced IC... | |||
T35843 | 9(R)-HODE cholesteryl ester | ||
9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... | |||
T35853 | 9(S)-HODE cholesteryl ester | ||
9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... | |||
T35846 | 13(R)-HODE cholesteryl ester | ||
13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid ... | |||
T25943 | Phenazoviridin | ||
Phenazoviridin is a newly discovered microbial free radical scavenger isolated from the culture medium of Streptomyces HR04. It is an anti-hypoxic compound with strong inhibitory activity against lipid peroxidation in ra... | |||
T81120 | SP4f | PPAR | |
SP4f, an activator of PPAR-γ, exhibits an EC50 value of 826 nM in HK-2 cells. In Swiss albino mice, it diminishes blood glucose levels and lipid peroxidation while enhancing glutathione levels and catalase activity [1]. | |||
T36160 | 8-iso Prostaglandin E2 | 8-iso Prostaglandin E2 | |
8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with ... | |||
T36558 | (±)9-HETE | ||
(±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC.... | |||
T68909 | Detorubicin Free Base | ||
Detorubicin Free Base is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication ... | |||
T68948 | Detorubicin HCl | ||
Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair... | |||
T67870 | DKI5 | (E)-N'-benzylidenehydrazinecarbothiohydrazide | Lipoxygenase |
DKI5 ((E)-N'-benzylidenehydrazinecarbothiohydrazide) is a LOX-1 inhibitor with an IC50 value of 22.5 μM.DKI5 may have anti-inflammatory and antioxidant activities and has shown anti-lipid peroxidation activity in in vitr... | |||
T35962 | MitoPBN | ||
MitoPBN is a mitochondria-targeted antioxidant. It accumulates in the mitochondria following the generation of a mitochondrial membrane potential by succinate, an effect that is blocked by addition of the mitochondrial m... | |||
T35993 | Epitalon (acetate) | ||
Epitalon is a synthetic tetrapeptide with anti-aging properties.1,2,3,4 Dietary administration of epitalon (0.00001% w/w) reduces levels of lipid peroxidation products in aged D. melanogaster tissue homogenates.1 Epitalo... | |||
T62347 | MPO-IN-5 | ||
MPO-IN-5 is a potent, irreversible inhibitor of MPO (myeloperoxidase). MPO-IN-5 inhibits MPO peroxidation (IC50: 0.22 μM) and hERG binding (IC50: 2.8 μM). 23000 M 1s 1. | |||
T36003 | 1(R)-(Trifluoromethyl)oleyl alcohol | ||
1(R)-(Trifluoromethyl)oleyl alcohol is an analog of oleic acid .1It inhibits ferroptosis induced by erastin in primary fibroblasts isolated from patients with Friedreich ataxia, a neuro- and cardiodegenerative disorder c... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T19161 | 7α-Hydroxycholesterol | Others | |
7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation. | |||
T7982 | 3,6-Dihydroxyflavone | Others | |
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway. | |||
TN2158 | Robinetin | 3,3',4',5',7-Pentahydroxyflavone | Anti-infection , HIV Protease , Antibacterial |
Robinetin (3,3',4',5',7-Pentahydroxyflavone) has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency. | |||
T0626 | Uric Acid | 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate | Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase |
Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ... | |||
T37710 | 5-Hydroxyoxindole | Reactive Oxygen Species | |
5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit... | |||
TN4973 | Sculponeatin O | Others | |
Sculponeatin O may have protective effects on the lipid peroxidation-damaged live cells. | |||
TN1863 | Licoisoflavone A | Phaseoluteone | MRP |
Licoisoflavone A (Phaseoluteone) is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM. | |||
TN4972 | Sculponeatin N | Others | |
Sculponeatin N may have protective effects on the lipid peroxidation-damaged live cells. | |||
TN2374 | Methyl Linolenate | Linolenic acid methyl ester | Others |
Methyl Linolenate (Linolenic acid methyl ester) is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. | |||
TN3120 | 5-Hydroxy-7-acetoxy-8-methoxyflavone | Histone Demethylase , Antiviral | |
5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity. | |||
T3S0289 | Araloside X | Calcium Channel | |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox... | |||
TN1962 | Myricetin 3-O-galactoside | Myricetin 3-O-beta-D-galactopyranoside | NOS , Xanthine Oxidase |
Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) can inhibit xanthine oxidase (xanthine oxidase; XO) activity, lipid peroxidation and scavenging free radicals. Myricetin 3-O-galactoside has many effects... | |||
TN2008 | Okanin | NF-κB , TLR | |
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect. | |||
TN2967 | Pinobanksin 3-acetate | 3-O-Acetylpinobanksin | Others , Antioxidant |
Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation. | |||
T4241 | Rubiadin | 1,3-Dihydroxy-2-Methylanthracene-9,10-Dione | Free radical scavengers , PARP , Caspase |
Rubiadin (1,3-Dihydroxy-2-Methylanthracene-9,10-Dione) possesses potent antioxidant property, it can prevent lipid peroxidation induced by FeSO4 and t-butylhydroperoxide (t-BHP) in a dose dependent manner. | |||
TN1644 | Flavanomarein | Others | |
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea... | |||
T19792 | 1,3,7-Trimethyluric acid | Others | |
1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi... | |||
T0131 | Cepharanthine | NSC-623442 | Apoptosis , TNF , HIV Protease , Autophagy |
Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production. | |||
T5S0636 | Citric acid | Citro,Citretten | Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic |
1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili... | |||
T5S1285 | (+)-(3R,8S)-Falcarindiol | Falcarindiol | Others |
1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a nov... | |||
TN1725 | Hederacolchiside E | Beta Amyloid , ROS | |
Hederacolchiside E has antioxidant activity and shows neuroprotective effects in Alzheimer's disease (AD) models via modulating oxidative stress. Hederacolchiside E exhibits inhibition on lipid peroxidation of linoleic a... | |||
TN1624 | Ethyl cinnamate | Calcium Channel , ROS , NO Synthase | |
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl... | |||
T4868 | Gamma-Linolenic acid | gamolenic acid,γ-Linolenic acid | Endogenous Metabolite |
gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced r... | |||
T3415 | Secoisolariciresinol diglucoside | LGM2605 | ROS |
Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ... | |||
TJS0315 | 4-Methyldaphnetin | 7,8-Dihydroxy-4-methylcoumarin,DHMC | Apoptosis , Lipoxygenase |
4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydr... | |||
T2O2741 | Thiamine monochloride | Thiamine chloride,Vitamin B1 | Others , Antioxidant , Endogenous Metabolite , Antibacterial |
Thiamine monochloride (Vitamin B1) is an essential vitamin with erythropoietic, glucose-regulatory, antioxidant, and mood-regulatory properties.Thiamine monochloride inhibits lead-induced lipid peroxidation, thereby prev... | |||
T41242 | Uric acid sodium | Reactive Oxygen Species | |
Uric acid sodium, scavengers of oxygen radicals, is a potent and common antioxidant that helps maintain stable blood pressure and resist oxidative stress. Uric acid sodium, which removes reactive oxygen species (ROS) suc... | |||
T2924 | Phloretin | Dihydronaringenin,NSC 407292,RJC 02792 | SGLT , transporter , Endogenous Metabolite |
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav... | |||
T5S1097 | Neferine | (R)-1,2-Dimethoxyaporphine,(-)-Neferine | Apoptosis , NF-κB , Autophagy |
1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to a... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
TN4406 | Lamiide | ||
Lamiide has anti-inflammatory activity in carrageenin-induced paw edema test. It shows lipid peroxidation inhibition on rat-brain phospholipid peroxidation. | |||
TN3069 | 4beta-Carboxy-19-nortotarol | NADPH-oxidase | |
4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not genera... | |||
T3S2210 | Lancerin | Others | |
Lancerin, extracted from the root bark of Cudrania cochinchinensis, exhibits antioxidative activity against lipid peroxidation. | |||
TN1588 | Dihydroisotanshinone I | ATPase , Potassium Channel , Calcium Channel | |
Dihydroisotanshinone I has protective action against menadione-induced hepatotoxicity, attributed to its antioxidant properties including the free radical scavenging activity and inhibition of lipid peroxidation. | |||
TN1896 | Luteolin 5-O-glucoside | Luteollin 5-glucoside | Others |
Luteolin 5-O-α2-glucopyranoside has antioxidant activity, it can inhibit lipid peroxidation, and has DPPH radical-scavenging activity. | |||
T74201 | 3′-Hydroxy-4′-O-methylglabridin | ||
3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1]. | |||
TN4770 | Phyllostadimer A | Others | |
Phyllostadimer A can significantly inhibit liposomal lipid peroxidation. | |||
T40368 | 4-Ethylresorcinol | ||
4-Ethylresorcinol, a derivative of resorcinol, functions as a tyrosinase substrate, possesses hypopigmentary effects, attenuates mRNA and protein expression of tyrosinase-related protein-2 (TRP-2), and exhibits antioxida... | |||
T31102 | Cryptopine | NSC32984,Kryptocavin,Cryptocavine,Kryptopine,Cryptopin | |
Cryptopine in vivo disturbs the cellular defense system, so that it tips in the direction of autoxidative lipid peroxidation, producing cytotoxicity. | |||
T13521 | 6"-O-Acetyldaidzin | Others | |
6-O-Acetyldaidzin is an isoflavone glycoside isolated from soybeans. It significantly inhibits lipid peroxidation in rat liver microsome (IC50: 8.2 μM). | |||
T14062 | 6"-O-Acetylgenistin | Others | |
6-O-Acetylgenistin is an isoflavone glycoside isolated from soybeans. 6-O-Acetylgenistin significantly inhibits lipid peroxidation in rat liver microsome with an IC50 of 10.6 μM[1][2]. | |||
T74202 | Hispaglabridin A | ||
Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1]. | |||
T81325 | Quercetin 3-O-rutinoside-7-O-glucoside | ||
Quercetin 3-O-rutinoside-7-O-glucoside (compound 8), an antioxidant present in Hemerocallis fulva, exhibits potent inhibitory action against lipid peroxidation [1]. | |||
T82278 | Glyurallin B | ||
Glyurallin B, a flavonoid derived from Glycyrrhiza inflata and Glycyrrhiza uralensis (licorice), exhibits ABTS+ radical scavenging activity and lipid peroxidation inhibition, with EC50 values of 11.9 ± 0.58 μM and 15.3 ±... | |||
TN4388 | Kielcorin | Antifection | |
Kielcorin shows antibacterial activity against strain EMRSA-16. It also shows in vitro anti-inflammatory (respiratory burst) inhibiting activities using isolated human neutrophils (IC (50) = 965.21 ± 65.80 uM). trans-Kie... | |||
TN4212 | Hirsutanonol | COX , Antifection | |
Hirsutanonol is a secondary metabolite from the bark of Alnus glutinosa. Hirsutanonol has potent antioxidant and free radical scavenging activities and exhibits an inhibition effect on mitochondrial lipid peroxidation. H... | |||
TN4877 | Quercetin 3,4'-dimethyl ether | ERK , BCL , MAPK , Caspase , JNK | |
Quercetin 3,4'-dimethyl ether shows anti-lipid peroxidation activity (IC 50 values of 0.3 uM), it also shows anti-inflammatory activity. Quercetin 3,4'-dimethyl ether could be useful in the development of novel anticance... | |||
TN2876 | 3,4-Dihydroxy-2-methoxyxanthone | Antibacterial , Antifection | |
3,4-Dihydroxy-2-methoxyxanthone shows antibacterial, and hepatoprotective activities, it can prevent tert-butylhydroperoxide-induced lipid peroxidation and cell death in freshly isolated rat hepatocytes and is effective ... | |||
T72594 | Broussochalcone A | ||
Broussochalcone A, an antioxidant and Xanthine Oxidase inhibitor (IC 50 =2.21 μM), exhibits free radical scavenging activity. It prevents iron-induced lipid peroxidation and nitric oxide synthesis in lipopolysaccharide (... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-01588 | ALDH7A1 Protein, Human, Recombinant (His) | Human | E. coli |
ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol... | |||
TMPY-02582 | Ferritin light chain Protein, Human, Recombinant (His) | Human | E. coli |
Ferritin, light polypeptide (FTL) is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light... | |||
TMPY-02299 | ALDH3A1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (... |
カタログ番号 | 製品名 | ||
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L8700 | Ferroptosis Compound Library | 779 compounds | |
A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; |