store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.
説明 | 5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM. |
ターゲット&IC50 | FLT3:170 nM, VEGFR2:52 nM, PDGFRβ:340 nM, VEGFR3:110 nM, MEK1:411 nM, TAK1:8.1 nM, B-Raf (VE):6300 nM, Src:6600 nM |
別名 | FR148083, L783279, LL-Z 1640-2 |
分子量 | 362.37 |
分子式 | C19H22O7 |
CAS No. | 253863-19-3 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 40 mg/mL (110.38 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
5Z-7-Oxozeaenol 253863-19-3 Angiogenesis MAPK Microbiology/Virology Tyrosine Kinase/Adaptors MEK FLT VEGFR PDGFR Antibiotic Src Vascular endothelial growth factor receptor L 783279 MAP kinase kinase kinase, MEKK, MAPKKK inhibit FR148083 5Z7Oxozeaenol L-783279 FR 148083 FR-148083 L783279 5Z 7 Oxozeaenol Inhibitor LL-Z 1640-2 MAP3K inhibitor