Powder: -20°C for 3 years | In solvent: -80°C for 1 year
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively. 6-Acetonyldihydrochelerythrine is a potent inducer of apoptosis in HCT116 and SW620 cell lines, it displays potent cytotoxic activity in human HCT116 and SW620 colon carcinoma cells, to a higher extent than 5-fluorouracil (5-FU), the cornerstone chemotherapeutic agent in colon cancer.
説明 | 6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therapeutic Index) values of 1.77 microg/mL and 14.6, respectively. 6-Acetonyldihydrochelerythrine is a potent inducer of apoptosis in HCT116 and SW620 cell lines, it displays potent cytotoxic activity in human HCT116 and SW620 colon carcinoma cells, to a higher extent than 5-fluorouracil (5-FU), the cornerstone chemotherapeutic agent in colon cancer. |
植物由来 |
分子量 | 405.44 |
分子式 | C24H23NO5 |
CAS No. | 22864-92-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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6-Acetonyldihydrochelerythrine 22864-92-2 Apoptosis Cytoskeletal Signaling DNA Damage/DNA Repair MAPK Metabolism Microbiology/Virology PI3K/Akt/mTOR signaling Proteases/Proteasome ERK BCL Akt HIV Protease PPAR p53 6 Acetonyldihydrochelerythrine 6Acetonyldihydrochelerythrine Inhibitor inhibitor inhibit