Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 24,500 | |||
5 mg | 在庫あり | ¥ 52,500 | |||
10 mg | 在庫あり | ¥ 91,500 | |||
25 mg | 在庫あり | ¥ 150,000 | |||
50 mg | 在庫あり | お問い合わせ |
説明 | Dehydroeffusol (Dehydro Effusol) possesses anti-cancer, anxiolytic and sedative properties. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. |
In vitro | Dehydroeffusol selectively activated the intracellular tumor suppressive stress response by promoting the overexpression of the key ER stress marker DNA damage-inducible transcript 3 (DDIT3), through upregulation of activating transcription factor 4 (ATF4). Concurrently, Dehydroeffusol suppressed the expression of the cell survival and ER stress marker glucose regulated protein of molecular mass 78 (GRP78) via downregulation of the transcription factor ATF6. In addition, Dehydroeffusolmarkedly activated the stress response signaling pathway MEKK4-MKK3/6-p38-DDIT3, but significantly inhibited ERK signaling[1]. |
植物由来 |
別名 | 5-Ethenyl-1-Methylphenanthrene-2,7-Diol, Dehydro Effusol |
分子量 | 250.29 |
分子式 | C17H14O2 |
CAS No. | 137319-34-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Dehydroeffusol 137319-34-7 Endocrinology/Hormones GPCR/G Protein MAPK Others Proteases/Proteasome MMP ERK GPR inhibit Inhibitor Apoptosis 5-Ethenyl-1-Methylphenanthrene-2,7-Diol Dehydro Effusol inhibitor