Powder: -20°C for 3 years | In solvent: -80°C for 1 year
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 約 35 days | ¥ 33,000 |
5 mg | 約 35 days | ¥ 150,500 |
10 mg | 約 35 days | ¥ 282,500 |
In vivo | In vivo, B cells lacking EBI2 or normal B cells rendered insensitive through pre-treatment with 7α,25-Dihydroxycholesterol (1 μM; 1.5 hours) display decreased migration to spleen follicular regions[1]. |
別名 | 7α,25-OHC |
分子量 | 418.65 |
分子式 | C27H46O3 |
CAS No. | 64907-22-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1 mg/mL (2.39 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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7α,25-Dihydroxycholesterol 64907-22-8 GPCR/G Protein Metabolism EBI2/GPR183 Endogenous Metabolite endogenous response 7a,25-OHC oxysterols 7a,25-Dihydroxycholesterol 7alpha,25-Dihydroxycholesterol GPCR ligand 7α,25 Dihydroxycholesterol receptor Inhibitor immune 7alpha,25-OHC migration 7α,25Dihydroxycholesterol cells 7α,25-OHC inhibit inhibitor