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Search Results for " response "

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463

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84

天然化合物

418

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17

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カタログ番号 製品名 別名 ターゲット
T23189 Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] Others
Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.
T4304 Azoramide Apoptosis , PERK
Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.
T1767 BMH-21 BMH21 DNA/RNA Synthesis
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
T23384 SR 11302 DNA/RNA Synthesis
SR 11302 is an inhibitor of activator protein-1 (AP-1).
T8464 RA-9 Apoptosis , DUB
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.
T9110 Ceapin-A7 Others
Ceapin-A7, with an IC50 of 0.59 μM, selectively inhibits ATF6α signaling in response to ER stress. This compound is instrumental in investigating ATF6α's activation mechanism and its function in pathological conditions.
T9349 IXA4 IRE1
IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function.
T6828 ZL0420 Epigenetic Reader Domain
ZL0420 is a potent and selective bromodomain-containing protein 4 ( BRD4 ) inhibitor with nanomolar binding affinities to bromodomains (BDs) of BRD4. ZL0420 has IC 50 values of 27 nM against BRD4 BD1 and 32 nM against B...
T3594 ML346 HSP
ML346 is a novel activator of Hsp70.
T64336 Izilendustat HIF/HIF Prolyl-Hydroxylase
Tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate inhibit of human recombinant EGLN-1 as substrate after 20 mins by mass spectrophotometric analysis.
T12579 RAMB4 PTP1B-IN-9 Proteasome
RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.
T9149 2BAct 2B-Act,2B Act PERK
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
T14141 AGI-24512 Others , Methionine Adenosyltransferase (MAT)
AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro.
T1814 ICILIN AG-3-5 TRP/TRPV Channel
ICILIN (AG-3-5) is a synthetic TRPM8 ion channel super-agonist.
T7318 Elimusertib BAY-1895344 ATM/ATR
Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the target...
T6859 I-BRD9 GSK602 Epigenetic Reader Domain
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.
T1269 Tripelennamine hydrochloride Pyribenzamine hydrochloride,Tripelennamine HCl,Pyribenzamine HCl Histamine Receptor
Tripelennamine hydrochloride (Pyribenzamine hydrochloride) is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation.
T3146 BMS-202 PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2 Apoptosis , PD-1/PD-L1
BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.
T14364 AZ-Dyrk1B-33 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine DYRK
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
T5954 Methyldopa hydrate Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate Dopamine Receptor , Adrenergic Receptor
Methyldopa hydrate (MK-351 hydrate) is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system, decreases production of dopamine, ...
T21584 CP 465022 iGluR
CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kainate-induced response with an IC50 of 25 nM in rat cortical ...
T20319 Pentabromophenol NSC 5717,NSC5717,NSC-5717 TGF-beta/Smad
Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.
T4032 MSX-127 MSX 127 CXCR
MSX-127 elicites positive response in peptide CXCR4.
T27064 CP-312 CP312,Cardioprotectant 312 Reactive Oxygen Species , Autophagy
CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1...
T1832 Walrycin B Antibacterial , Antibiotic
Walrycin B is a new-type antibacterial compound targeting the WalR response regulator.
T10733 CDDO-EA TP319,CDDO ethyl amide,RTA 405 Nrf2
CDDO-EA (CDDO ethyl amide) is an activator of the Nrf2/antioxidant response element.
T7297 KG-501 Naphthol AS-E phosphate Epigenetic Reader Domain
KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).
T39980 ErSO Others
ErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.
TP1029 Thymalfasin Thymosin α1 Others
Thymalfasin (Thymosin α1) (thymosin-alpha 1) is an immunomodulating agent able to enhance the Thl immune response.
T23383 SR11237 SR 11237 Others , RAR/RXR 
SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR/RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.
TQ0076 KIRA6 IRE1
KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response.
T67783 Trans-isrib A17 ISR-IN-1 Others
trans-isrib A17 (ISR-IN-1) is an potent inhibitor of the integrated stress response with EC50 of 0.6 nM.
T67756 ISRIB-A15 ISR-IN-2 Others
ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
T21444 Diphenylcyclopropenone DPCP,Diphencyprone Others
Diphenylcyclopropenone (DPCP) is a topical drug used to treat alopecia areata, alopecia totalis, and refractory warts. Diphencyprone acts as a local stimulator that triggers an immune response against the action of autor...
T10389L Aspartyl-alanyl-diketopiperazine acetate DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base) Others
Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy.
T11318 Dopexamine hydrochloride FPL60278AR Adrenergic Receptor
Dopexamine hydrochloride (FPL60278AR) is a β2-adrenergic receptor agonist. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regi...
T9343 N-Cbz-DL-tryptophan cholecystokinin
N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8.
T20224 L-Dithiothreitol L-Dtt Others
L-Dithiothreitol (L-Dtt) is a chiral bidentate dithiol with two stereogenic centers. It may be used in chiroptical response research.
T29842 Alclofenac W 7320,MY 101,BRN 2116510,W-7320,W7320 Others
Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism.
T14842 BW 245C BW245C Prostaglandin Receptor
BW 245C is a selective prostaglandin-like DP receptor (DP1) agonist, a prostaglandin analogue with inhibitory effects on the aggregation response of collagen, which can be used to study diseases such as stroke.
T9545 Compound 1T-0219 (SC) FAK
Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylati...
T23284 Ryuvidine Histone Demethylase , Histone Methyltransferase , CDK
Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response with potential anticancer activity, inhibition of H4K20 methylation, and inhibition of CDK4, and can be used to study breast cancer ...
T7845 BTZO-1 Apoptosis
BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
T5364 TBHQ tert-Butylhydroquinone Apoptosis , ERK , Others , Ferroptosis , Nrf2 , Autophagy
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.
T25705 Imupedone LF1695,LF-1695,LF 1695 Others
Imupedone (LF 1695) is a synthetic immunomodulator that modulates T lymphocytes and macrophages, induces T-cell differentiation of bone marrow precursor cells, and increases the proliferative response of lymphocytes to m...
T23974 DDRI-18 DDRI18,DDRI 18 DNA/RNA Synthesis
DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joining (NHEJ) DNA repair and enhances the cytotoxicity of antica...
T0134 Imiquimod R 837,S-26308 SARS-CoV , TLR , Autophagy , HSV
Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist.
T9721 ML339 CXCR
ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.
T4680 HC-067047 HC067047 TRP/TRPV Channel
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .
T74140 β-D-Glucan Others
β-D-Glucan is a compound that targets tumor-associated macrophages with antitumor activity and modulates the immune response in necrotizing pancreatitis.

Compounds

prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]
T23189
Synonym:
Target: Others
Azoramide
T4304
Synonym:
Target: Apoptosis, PERK
BMH-21
T1767
Synonym: BMH21
Target: DNA/RNA Synthesis
SR 11302
T23384
Synonym:
Target: DNA/RNA Synthesis
RA-9
T8464
Synonym:
Target: Apoptosis, DUB
Ceapin-A7
T9110
Synonym:
Target: Others
IXA4
T9349
Synonym:
Target: IRE1
ZL0420
T6828
Synonym:
Target: Epigenetic Reader Domain
ML346
T3594
Synonym:
Target: HSP
Izilendustat
T64336
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase
RAMB4
T12579
Synonym: PTP1B-IN-9
Target: Proteasome
2BAct
T9149
Synonym: 2B-Act,2B Act
Target: PERK
AGI-24512
T14141
Synonym:
Target: Others, Methionine Adenosyltransferase (MAT)
ICILIN
T1814
Synonym: AG-3-5
Target: TRP/TRPV Channel
Elimusertib
T7318
Synonym: BAY-1895344
Target: ATM/ATR
I-BRD9
T6859
Synonym: GSK602
Target: Epigenetic Reader Domain
Tripelennamine hydrochloride
T1269
Synonym: Pyribenzamine hydrochloride,Tripelennamine HCl,Pyribenzamine HCl
Target: Histamine Receptor
BMS-202
T3146
Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2
Target: Apoptosis, PD-1/PD-L1
AZ-Dyrk1B-33
T14364
Synonym: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
Target: DYRK
Methyldopa hydrate
T5954
Synonym: Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate
Target: Dopamine Receptor, Adrenergic Receptor
CP 465022
T21584
Synonym:
Target: iGluR
Pentabromophenol
T20319
Synonym: NSC 5717,NSC5717,NSC-5717
Target: TGF-beta/Smad
MSX-127
T4032
Synonym: MSX 127
Target: CXCR
CP-312
T27064
Synonym: CP312,Cardioprotectant 312
Target: Reactive Oxygen Species, Autophagy
Walrycin B
T1832
Synonym:
Target: Antibacterial, Antibiotic
CDDO-EA
T10733
Synonym: TP319,CDDO ethyl amide,RTA 405
Target: Nrf2
KG-501
T7297
Synonym: Naphthol AS-E phosphate
Target: Epigenetic Reader Domain
ErSO
T39980
Synonym:
Target: Others
Thymalfasin
TP1029
Synonym: Thymosin α1
Target: Others
SR11237
T23383
Synonym: SR 11237
Target: Others, RAR/RXR 
KIRA6
TQ0076
Synonym:
Target: IRE1
trans-isrib A17
T67783
Synonym: ISR-IN-1
Target: Others
ISRIB-A15
T67756
Synonym: ISR-IN-2
Target: Others
Diphenylcyclopropenone
T21444
Synonym: DPCP,Diphencyprone
Target: Others
Aspartyl-alanyl-diketopiperazine acetate
T10389L
Synonym: DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)
Target: Others
Dopexamine hydrochloride
T11318
Synonym: FPL60278AR
Target: Adrenergic Receptor
N-Cbz-DL-tryptophan
T9343
Synonym:
Target: cholecystokinin
L-Dithiothreitol
T20224
Synonym: L-Dtt
Target: Others
Alclofenac
T29842
Synonym: W 7320,MY 101,BRN 2116510,W-7320,W7320
Target: Others
BW 245C
T14842
Synonym: BW245C
Target: Prostaglandin Receptor
Compound 1T-0219 (SC)
T9545
Synonym:
Target: FAK
Ryuvidine
T23284
Synonym:
Target: Histone Demethylase, Histone Methyltransferase, CDK
BTZO-1
T7845
Synonym:
Target: Apoptosis
TBHQ
T5364
Synonym: tert-Butylhydroquinone
Target: Apoptosis, ERK, Others, Ferroptosis, Nrf2, Autophagy
Imupedone
T25705
Synonym: LF1695,LF-1695,LF 1695
Target: Others
DDRI-18
T23974
Synonym: DDRI18,DDRI 18
Target: DNA/RNA Synthesis
Imiquimod
T0134
Synonym: R 837,S-26308
Target: SARS-CoV, TLR, Autophagy, HSV
ML339
T9721
Synonym:
Target: CXCR
HC-067047
T4680
Synonym: HC067047
Target: TRP/TRPV Channel
β-D-Glucan
T74140
Synonym:
Target: Others
1 2 3 4 5 6 7 8 9 10
カタログ番号 製品名 別名 ターゲット
T5043 Lentinan Others
Lentinan, isolated and purified from a hot water extract of Lentinula edodes fruit bodies, is a fungal polysaccharide immunomodulator with anti-tumor effects.
T4940 3-Methylhistamine dihydrochloride Others , Endogenous Metabolite
N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere...
TQ0302 Thapsigargin Apoptosis , SARS-CoV , Calcium Channel
Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking ...
T1399 Sucralose Trichlorosucrose,E955 Others , Endogenous Metabolite
Sucralose (Trichlorosucrose), an artificial sweetener, is not degraded by the body, so it is noncaloric.
T0505 Methyldopa L-(-)-α-Methyldopa,MK-351 Dopamine Receptor , Adrenergic Receptor
Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic.
TQ0211 Brusatol (+)-Brusatol,NSC 172924 Others , Ferroptosis , Nrf2
Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.
TQ0251 (Z)-2-decenoic acid (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid Others
(Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria. ...
T14063 7α,25-Dihydroxycholesterol 7α,25-OHC EBI2/GPR183 , Endogenous Metabolite
T3395 Timosaponin AIII Filiferin B,AneMarsaponin A3,Timosaponin A3 AChE , mTOR
Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC...
T37101 1-Hydroxyanthraquinone DNA/RNA Synthesis
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
T5688 Micheliolide NOS , NF-κB , COX
Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.
T6S0109 Sipeimine Kashmirine,Imperialine Others
1. Sipeimine (Kashmirine) has antiasthmatic effect, on tracheal M receptor antagonist. 2. Sipeimine can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve to the right.
T34295 Resiniferatoxin RTX,[3H]resiniferatoxin IL Receptor
Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response.
T13693 Fibrin Others
Fibrin, the primary constituent of blood clots, is an insoluble protein essential for coagulation. Isolated from bovine blood, this protein is notably synthesized in response to bleeding.
T3S1692 Octahydrocurcumin Anti-infection , NF-κB , Reactive Oxygen Species , ROS
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...
T5S2245 Alisol C 23-acetate Alisol C monoacetate Others
Alisol C 23-acetate (Alisol C monoacetate) is a natural product isolated from Alisma orientale, can significantly and strongly inhibit DTH response after oral administration,has antibacterial activity.
TN1425 Bacoside A3 ATPase , ROS , P-gp
Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
T5729 L-quebrachitol Wnt/beta-catenin
L-quebrachitol is a natural product.L-quebrachitol may promote osteoblastogenesis by triggering the BMP-2-response as well as the Runx2, MAPK, and Wnt/β-catenin signaling pathway.
T5S1897 Linderalactone Apoptosis , Others , JAK
1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.
TN3174 6-Methoxyflavanone NSC50184 GABA Receptor
6-Methoxyflavanone (6-MeOF) is A positive allosteric modulator of the GABA response of human recombinant GABA A receptor, with antianxiety and anti-inflammatory activity, and can be used to reduce cisplatin induced neuro...
T4A2462 Telocinobufagin Telobufotoxin,Telocinobufogenin Others
1. Telocinobufagin (Telobufotoxin) is the major endogenous digitalis-like factor. 2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice chall...
TCS1704 Artemitin Artemetin,Artemisetin,Erianthin Antioxidant
1. Artemitin (Erianthin) has anti-inflammatory activity. 2. Artemitin (Erianthin) protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. 3. Intravenou...
T10065L 2',3'-cGAMP sodium 2'-3'-cyclic GMP-AMP sodium STING , cGAS
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm...
T5764 Alliin (S)-3-(Allylsulphinyl)-L-alanine NF-κB , PPAR
Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS...
T3S1873 Talatisamine Potassium Channel
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talat...
T11855 Lipopolysaccharides LPS Others
Lipopolysaccharides (LPS) is a natural product, an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides are highly immunogenic antigens that enhance the immune res...
T5S0993 Kurarinone BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameli...
T7033 Rosmanol Antioxidant , COX
Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and a...
T2563 Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride Others , Endogenous Metabolite
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...
T2S0731 Trilobatin P-Phlorizin Amylase
Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon...
TWS1977 Kamebakaurin Kamebakaurine NF-κB
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...
T5S1889 Yunaconitine Guayewuanine B Others
1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows po...
T3893 Forsythoside B TNF , NF-κB
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...
T20879 Tacrolimus monohydrate FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 Phosphatase , Others , Antibacterial , Antibiotic , Autophagy
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi...
T3S1701 Dihydrocurcumin PPAR , Fatty Acid Synthase
Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, incr...
T1183 Retinol all-trans-Retinol,Vitamin A,Vitamin A1,Alphalin Others
Retinol (Alphalin) and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune r...
T5S0167 Atractylenolide I IL Receptor , TNF , TLR , JAK , STAT
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide...
T5S0018 Betulonic acid (+)-Betulonic acid,Betunolic acid,Liquidambaric acid Parasite , HSV
1. Betulonic acid (Liquidambaric acid) amide stimulated the regenerative response in hepatocytes under conditions of combined toxic exposure and promoted recovery of their qualitative and quantitative characteristics, wh...
TMS1461 Qingyangshengenin B Otophylloside B Beta Amyloid
Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mR...
T4S1469 Cucurbitacin IIb Apoptosis , Others
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i...
T5065 GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD Monosodium-GMP,cGMP sodium salt,Cyclic GMP PKA
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc...
T2915 Bardoxolone RTA 401,CDDO Others , Nrf2
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...
T1168 Desonide Tridesilon,Locapred,Prednacinolone Glucocorticoid Receptor
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ...
T6S1699 Shogaol [6]-Shogaol,6-Shogaol Lipoxygenase , Autophagy
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...
T6S1917 Schisandrol B Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B P450 , Reactive Oxygen Species , Autophagy
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...
T3929 Kaurenoic acid Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid Others
Kaurenoic acid (kaurenoate) has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level. Kaurenoic acid exerts a uterine relaxant effect acting principally through calcium blockade and in part,...
T5074 Cholesteryl palmitate Others , Endogenous Metabolite
Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a ...
T38373 2-heptyl-3-hydroxy-4(1H)-Quinolone 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal Others
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...
T3S1612 Kuwanon G Moracenin B,Kuwanone G Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
T2S2264 Linalool Linalol,(±)-Linalool,Phantol Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
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天然物製品

Lentinan
T5043
Synonym:
Target: Others
3-Methylhistamine dihydrochloride
T4940
Synonym:
Target: Others, Endogenous Metabolite
Thapsigargin
TQ0302
Synonym:
Target: Apoptosis, SARS-CoV, Calcium Channel
Sucralose
T1399
Synonym: Trichlorosucrose,E955
Target: Others, Endogenous Metabolite
Methyldopa
T0505
Synonym: L-(-)-α-Methyldopa,MK-351
Target: Dopamine Receptor, Adrenergic Receptor
Brusatol
TQ0211
Synonym: (+)-Brusatol,NSC 172924
Target: Others, Ferroptosis, Nrf2
(Z)-2-decenoic acid
TQ0251
Synonym: (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid
Target: Others
7α,25-Dihydroxycholesterol
T14063
Synonym: 7α,25-OHC
Target: EBI2/GPR183, Endogenous Metabolite
Timosaponin AIII
T3395
Synonym: Filiferin B,AneMarsaponin A3,Timosaponin A3
Target: AChE, mTOR
1-Hydroxyanthraquinone
T37101
Synonym:
Target: DNA/RNA Synthesis
Micheliolide
T5688
Synonym:
Target: NOS, NF-κB, COX
Sipeimine
T6S0109
Synonym: Kashmirine,Imperialine
Target: Others
Resiniferatoxin
T34295
Synonym: RTX,[3H]resiniferatoxin
Target: IL Receptor
Fibrin
T13693
Synonym:
Target: Others
Octahydrocurcumin
T3S1692
Synonym:
Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS
Alisol C 23-acetate
T5S2245
Synonym: Alisol C monoacetate
Target: Others
Bacoside A3
TN1425
Synonym:
Target: ATPase, ROS, P-gp
L-quebrachitol
T5729
Synonym:
Target: Wnt/beta-catenin
Linderalactone
T5S1897
Synonym:
Target: Apoptosis, Others, JAK
6-Methoxyflavanone
TN3174
Synonym: NSC50184
Target: GABA Receptor
Telocinobufagin
T4A2462
Synonym: Telobufotoxin,Telocinobufogenin
Target: Others
Artemitin
TCS1704
Synonym: Artemetin,Artemisetin,Erianthin
Target: Antioxidant
2',3'-cGAMP sodium
T10065L
Synonym: 2'-3'-cyclic GMP-AMP sodium
Target: STING, cGAS
Alliin
T5764
Synonym: (S)-3-(Allylsulphinyl)-L-alanine
Target: NF-κB, PPAR
Talatisamine
T3S1873
Synonym:
Target: Potassium Channel
Lipopolysaccharides
T11855
Synonym: LPS
Target: Others
Kurarinone
T5S0993
Synonym:
Target: BCL, Others, IκB/IKK, TNF, NF-κB, JAK, STAT
Rosmanol
T7033
Synonym:
Target: Antioxidant, COX
Acetyl-L-carnitine hydrochloride
T2563
Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride
Target: Others, Endogenous Metabolite
Trilobatin
T2S0731
Synonym: P-Phlorizin
Target: Amylase
Kamebakaurin
TWS1977
Synonym: Kamebakaurine
Target: NF-κB
Yunaconitine
T5S1889
Synonym: Guayewuanine B
Target: Others
Forsythoside B
T3893
Synonym:
Target: TNF, NF-κB
Tacrolimus monohydrate
T20879
Synonym: FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506
Target: Phosphatase, Others, Antibacterial, Antibiotic, Autophagy
Dihydrocurcumin
T3S1701
Synonym:
Target: PPAR, Fatty Acid Synthase
Retinol
T1183
Synonym: all-trans-Retinol,Vitamin A,Vitamin A1,Alphalin
Target: Others
Atractylenolide I
T5S0167
Synonym:
Target: IL Receptor, TNF, TLR, JAK, STAT
Betulonic acid
T5S0018
Synonym: (+)-Betulonic acid,Betunolic acid,Liquidambaric acid
Target: Parasite, HSV
Qingyangshengenin B
TMS1461
Synonym: Otophylloside B
Target: Beta Amyloid
Cucurbitacin IIb
T4S1469
Synonym:
Target: Apoptosis, Others
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD
T5065
Synonym: Monosodium-GMP,cGMP sodium salt,Cyclic GMP
Target: PKA
Bardoxolone
T2915
Synonym: RTA 401,CDDO
Target: Others, Nrf2
Desonide
T1168
Synonym: Tridesilon,Locapred,Prednacinolone
Target: Glucocorticoid Receptor
Shogaol
T6S1699
Synonym: [6]-Shogaol,6-Shogaol
Target: Lipoxygenase, Autophagy
Schisandrol B
T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
Kaurenoic acid
T3929
Synonym: Kauren-19-Oic Acid,kaurenoate,kaur-16-en-18-oic acid
Target: Others
Cholesteryl palmitate
T5074
Synonym:
Target: Others, Endogenous Metabolite
2-heptyl-3-hydroxy-4(1H)-Quinolone
T38373
Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal
Target: Others
kuwanon G
T3S1612
Synonym: Moracenin B,Kuwanone G
Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase
Linalool
T2S2264
Synonym: Linalol,(±)-Linalool,Phantol
Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-01659 SDPR Protein, Mouse, Recombinant (aa 2-180, His) Mouse E. coli
Serum deprivation-response protein, also known as Phosphatidylserine-binding protein, Cavin-2 and SDPR, is a member of the PTRF / SDPR family. SDPR is highly expressed in heart and lung, and expressed at lower levels in ...
TMPY-06624 STAT3 Protein, Human, Recombinant (His) Human E. coli
STAT3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 65.31 kDa and the accession number is P40763-1.
TMPY-03456 SRFBP1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in th...
TMPY-02248 Myocilin Protein, Human, Recombinant (His) Human HEK293 Cells
Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC, and GLC1A, is a protein that contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid o...
TMPH-00949 APOLD1 Protein, Human, Recombinant (His) Human E. coli
May be involved in angiogenesis. May play a role in activity-dependent changes of brain vasculature. May affect blood-brain permeability. APOLD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system...
TMPJ-00088 EFNA1 Protein, Mouse, Recombinant (hFc & His) Mouse HEK293 Cells
Ephrin-A1 is a cell membrane protein and contains 1 ephrin RBD (ephrin receptor-binding) domain. EFNA1 belongs to the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor ...
TMPJ-00883 EGR1 Protein, Human, Recombinant (His) Human E. coli
EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The produc...
TMPH-01227 DPYSL2 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the...
TMPH-01226 CRMP1 Protein, Human, Recombinant Human E. coli
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F...
TMPH-01228 DPYSL3 Protein, Human, Recombinant (His) Human E. coli
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
TMPJ-01312 TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it...
TMPJ-00700 GADD45B Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPJ-00546 EFNA1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPJ-01464 IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F) Human HEK293 Cells
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system,belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-02904 TLR4 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans...
TMPY-06981 IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) Human E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPK-01246 GDF-15 Protein, Mouse, Recombinant (His) Mouse E. coli
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPY-04310 Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His) Human HEK293 Cells
Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293 Cells
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-04552 AKT1 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPJ-00864 VEGF165 Protein, Human, Recombinant Human HEK293 Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-00322 DEC-205 Protein, Human, Recombinant (His) Human HEK293 Cells
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-04125 PTP1B Protein, Human, Recombinant (His) Human E. coli
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPJ-01465 GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) Human E. coli
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of...
TMPY-02953 TEM8/ANTXR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser...
TMPY-04572 MKK4 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus Insect Cells
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His) Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPJ-00387 IL-4R alpha Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPY-06983 IFN gamma Protein, Human, Recombinant (E. coli) Human E. coli
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ...
TMPY-01648 TREML2 Protein, Human, Recombinant (His) Human HEK293 Cells
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like...
TMPY-02869 MMP-12 Protein, Human, Recombinant (catalytic domain) Human E. coli
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPH-00589 SpoT Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme cataly...
TMPH-02585 ACOD1 Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory inna...
TMPH-00788 PYP Protein, Halochromatium salexigens, Recombinant (His) Halochromatium salexigens E. coli
Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.
TMPH-02856 SAAL1 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Plays a role in promoting the proliferation of synovial fibroblasts in response to proinflammatory stimuli.
TMPH-02937 TLR11 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. TLR11 Protein, Mouse, Recombinant (His & Myc) ...
TMPH-00646 LexA repressor Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA int...
TMPH-02614 CREB5 Protein, Mouse, Recombinant (His) Mouse E. coli
Binds to the cAMP response element and activates transcription.
TMPH-00077 IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc) Arabidopsis thaliana E. coli
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response fac...
TMPJ-00665 ADAMDEC1 Protein, Human, Recombinant (His) Human HEK293 Cells
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturati...
TMPH-01552 IRF1 Protein, Human, Recombinant (GST & His) Human Baculovirus Insect Cells
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections,...
TMPY-03854 TMED4 Protein, Human, Recombinant (His) Human HEK293 Cells
TMED4, also known as ERS25, belongs to the EMP24/GP25L family. TMED4 may play a role in the regulation of heat-shock response and apoptosis. It is involved in vesicular protein trafficking, mainly in the early secretory ...
TMPY-00342 TMED4 Protein, Human, Recombinant (mFc) Human HEK293 Cells
TMED4, also known as ERS25, belongs to the EMP24/GP25L family. TMED4 may play a role in the regulation of heat-shock response and apoptosis. It is involved in vesicular protein trafficking, mainly in the early secretory ...
TMPH-03207 IL-2 Protein, Rabbit, Recombinant (His) Rabbit E. coli
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes...
TMPH-01021 BTN3A1 Protein, Human, Recombinant (E. coli, His) Human E. coli
Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPH-02442 IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO) Rhesus E. coli
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes...
TMPH-01020 BTN3A1 Protein, Human, Recombinant (Yeast, His) Human P. pastoris (Yeast)
Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPH-02831 PLET1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
TMPH-01796 NR4A1 Protein, Human, Recombinant (His & Myc) Human E. coli
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B tr...
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SDPR Protein, Mouse, Recombinant (aa 2-180, His)
TMPY-01659
Species: Mouse
Expression System: E. coli
STAT3 Protein, Human, Recombinant (His)
TMPY-06624
Species: Human
Expression System: E. coli
SRFBP1 Protein, Human, Recombinant (His & GST)
TMPY-03456
Species: Human
Expression System: Baculovirus Insect Cells
Myocilin Protein, Human, Recombinant (His)
TMPY-02248
Species: Human
Expression System: HEK293 Cells
APOLD1 Protein, Human, Recombinant (His)
TMPH-00949
Species: Human
Expression System: E. coli
EFNA1 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00088
Species: Mouse
Expression System: HEK293 Cells
EGR1 Protein, Human, Recombinant (His)
TMPJ-00883
Species: Human
Expression System: E. coli
DPYSL2 Protein, Human, Recombinant (His)
TMPH-01227
Species: Human
Expression System: P. pastoris (Yeast)
CRMP1 Protein, Human, Recombinant
TMPH-01226
Species: Human
Expression System: E. coli
DPYSL3 Protein, Human, Recombinant (His)
TMPH-01228
Species: Human
Expression System: E. coli
TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)
TMPJ-01312
Species: Mouse
Expression System: HEK293 Cells
GADD45B Protein, Human, Recombinant (His)
TMPJ-00700
Species: Human
Expression System: E. coli
EFNA1 Protein, Human, Recombinant (hFc)
TMPJ-00546
Species: Human
Expression System: HEK293 Cells
IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
TMPJ-01464
Species: Human
Expression System: HEK293 Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
TLR4 Protein, Human, Recombinant (His)
TMPY-02904
Species: Human
Expression System: Baculovirus Insect Cells
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
TMPY-06981
Species: Human
Expression System: E. coli
GDF-15 Protein, Mouse, Recombinant (His)
TMPK-01246
Species: Mouse
Expression System: E. coli
Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)
TMPY-04310
Species: Human
Expression System: HEK293 Cells
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293 Cells
AKT1 Protein, Human, Recombinant (His)
TMPY-04552
Species: Human
Expression System: Baculovirus Insect Cells
VEGF165 Protein, Human, Recombinant
TMPJ-00864
Species: Human
Expression System: HEK293 Cells
DEC-205 Protein, Human, Recombinant (His)
TMPY-00322
Species: Human
Expression System: HEK293 Cells
PTP1B Protein, Human, Recombinant (His)
TMPY-04125
Species: Human
Expression System: E. coli
GM-CSF/CSF2 Protein, Human, Recombinant (E. coli)
TMPJ-01465
Species: Human
Expression System: E. coli
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
TMPY-02953
Species: Human
Expression System: HEK293 Cells
MKK4 Protein, Mouse, Recombinant (His & GST)
TMPY-04572
Species: Mouse
Expression System: Baculovirus Insect Cells
HtrA2/Omi Protein, Human, Recombinant (His)
TMPY-02078
Species: Human
Expression System: E. coli
IL-4R alpha Protein, Mouse, Recombinant (hFc)
TMPJ-00387
Species: Mouse
Expression System: HEK293 Cells
IFN gamma Protein, Human, Recombinant (E. coli)
TMPY-06983
Species: Human
Expression System: E. coli
TREML2 Protein, Human, Recombinant (His)
TMPY-01648
Species: Human
Expression System: HEK293 Cells
MMP-12 Protein, Human, Recombinant (catalytic domain)
TMPY-02869
Species: Human
Expression System: E. coli
SpoT Protein, E. coli, Recombinant (His & Myc)
TMPH-00589
Species: E. coli
Expression System: E. coli
ACOD1 Protein, Mouse, Recombinant (His & Myc)
TMPH-02585
Species: Mouse
Expression System: Baculovirus Insect Cells
PYP Protein, Halochromatium salexigens, Recombinant (His)
TMPH-00788
Species: Halochromatium salexigens
Expression System: E. coli
SAAL1 Protein, Mouse, Recombinant (His & Myc)
TMPH-02856
Species: Mouse
Expression System: E. coli
TLR11 Protein, Mouse, Recombinant (His & Myc)
TMPH-02937
Species: Mouse
Expression System: E. coli
LexA repressor Protein, E. coli, Recombinant (His & SUMO)
TMPH-00646
Species: E. coli
Expression System: E. coli
CREB5 Protein, Mouse, Recombinant (His)
TMPH-02614
Species: Mouse
Expression System: E. coli
IAA17 Protein, Arabidopsis thaliana, Recombinant (His & Myc)
TMPH-00077
Species: Arabidopsis thaliana
Expression System: E. coli
ADAMDEC1 Protein, Human, Recombinant (His)
TMPJ-00665
Species: Human
Expression System: HEK293 Cells
IRF1 Protein, Human, Recombinant (GST & His)
TMPH-01552
Species: Human
Expression System: Baculovirus Insect Cells
TMED4 Protein, Human, Recombinant (His)
TMPY-03854
Species: Human
Expression System: HEK293 Cells
TMED4 Protein, Human, Recombinant (mFc)
TMPY-00342
Species: Human
Expression System: HEK293 Cells
IL-2 Protein, Rabbit, Recombinant (His)
TMPH-03207
Species: Rabbit
Expression System: E. coli
BTN3A1 Protein, Human, Recombinant (E. coli, His)
TMPH-01021
Species: Human
Expression System: E. coli
IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO)
TMPH-02442
Species: Rhesus
Expression System: E. coli
BTN3A1 Protein, Human, Recombinant (Yeast, His)
TMPH-01020
Species: Human
Expression System: P. pastoris (Yeast)
PLET1 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02831
Species: Mouse
Expression System: E. coli
NR4A1 Protein, Human, Recombinant (His & Myc)
TMPH-01796
Species: Human
Expression System: E. coli
カタログ番号 製品名
L6710 Anti-Inflammatory Traditional Chinese Medicine Compound Library

1246 compounds
A collection of 1246 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study;
L9700 Endoplasmic Reticulum Stress Compound Library

193 compounds
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L1380 Transcription Factor-Targeted Compound Library

695 compounds
Well-chosen 695 compounds with unique structures targeting transcription factor;
L1400 MAPK Inhibitor Library

365 compounds
A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
L2400 Endocrinology-Hormone Compound Library

784 compounds
A unique collection of 784 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L1710 Anti-COVID-19 Compound Library

1133 compounds
A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents;
L8720 Pyroptosis Compound Library

1066 compounds
1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L8500 HIF-1 Signaling Pathway Compound Library

1336 compounds
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;
L2800 Serotonin Receptor-Targeted Compound Library

268 compounds
A unique collection of 268 compounds targeting serotonin receptors for high throughput screening and high content screening;
L9860 Antidepressant Compound Library

1163 compounds
1163 compounds associated with depression that can be used for high-throughput and high-content screening
L6140 Saccharide and Glycoside Natural Product Library

362 compounds
A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS;
L2540 Gut Microbial Metabolite Library

607 compounds
A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS;
L5510 Drug-induced Liver Injury (DILI) Compound Library

1001 compounds
A unique collection of 1001 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening;
L3800 NF-κB Signaling Compound Library

729 compounds
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L2170 Immuno-Oncology Compound Library

449 compounds
A unique collection of 449 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening;
L6750 PBCRBS Traditional Chinese Medicine Compound Library

580 compounds
A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.
L7110 Anti-Hypertension Compound Library

678 compounds
678 hypertension-related small molecules for high-throughput and high-content screening.