564
1174
58
7
1
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T83763 | EPI-X4 TFA | Endogenous Peptide Inhibitor of CXCR4 | |
EPI-X4, an endogenous peptide fragment of human serum albumin (amino acids 408-423), serves as an antagonist to the chemokine (C-X-C motif) receptor 4 (CXCR4). It effectively prevents calcium mobilization and receptor in... | |||
T5848 | Biocytin | Endogenous Metabolite | |
Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the ϵ-amine of L-lysine via a se... | |||
T13730 | Hydroxocobalamin acetate | Others | |
Hydroxocobalamin acetate is used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia. Hydroxocobalamin, an injectable naturally occurring form of vitamin B12 with a favorable ad... | |||
T22352 | L-Gulose | Others , Endogenous Metabolite | |
L-Gulose is an unnatural monosaccharide. L-Gulose is the putative furanose form of L-sorbosone that exists as a syrup with a sweet taste. It is an L-hexose sugar and an intermediate in the biosynthesis of L-Ascorbate (vi... | |||
T8104 | Glycyl-L-valine | Others , Endogenous Metabolite | |
Glycyl-L-valine is a dipeptide composed of glycine and valine. It is an incomplete breakdown product of protein digestion or protein catabolism. | |||
TP1442 | Neuromedin B | Endogenous Metabolite | |
Neuromedin B (NMB) is one of the bombesin (BN)-related peptides in mammals. It was originally purified from pig spinal cords, and it has been shown to be present in central nervous system as well as in gastrointestinal t... | |||
T10022 | 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine | Endogenous Metabolite | |
1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is an endogenous metabolite. 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is a non-limiting exemplary phosphatidyl choline. | |||
T7630 | Tuftsin | Tuftsin(3TFA) | Endogenous Metabolite |
Tuftsin (Tuftsin(3TFA)) is a natural activator of Phagocyte Cells | |||
T8037 | H-Phe-Phe-OH | Endogenous Metabolite | |
H-Phe-Phe-OH is a dipeptide consisting of two phenylalanine (an essential amino acid and precursor to tyrosine) units linked together. | |||
T9372 | D-Histidine | Mitochondrial Metabolism | |
D-Histidine is an enantiomer of L-histidine. L-Histidine is an inhibitor of mitochondrial glutamine transport and also an essential amino acid for infants. | |||
T22243 | Anserine | L-Anserine | Endogenous Metabolite |
Anserine (L-Anserine) is a dipeptide containing β-alanine and histidine, which can be found in the skeletal muscle and brain of mammals and birds. Anserine is not cleaved by serum carnosinase and act as biochemical buffe... | |||
T36787 | 2-hydroxymethyl benzoic acid | Endogenous Metabolite | |
2-hydroxymethyl benzoic acid is an endogenous metabolite. | |||
TP1087 | Substance P | Neurokinin P | Endogenous Metabolite , Neurokinin receptor |
Substance P (Neurokinin P) (SP) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) member of the tachykinin neuropeptide family. | |||
T31976 | Glymidine sodium | Others | |
Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion. | |||
T37859 | SY-640 | Endogenous Metabolite | |
TP1277 | Bradykinin | Endogenous Metabolite , Bradykinin Receptor | |
Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol... | |||
T7454 | 4-Bromo-3-hydroxybenzoic acid | Decarboxylase , Endogenous Metabolite | |
4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase. | |||
T7092 | NADPH tetrasodium salt | Others , Ferroptosis , Endogenous Metabolite | |
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an end... | |||
T7686 | Ramiprilat | RAAS | |
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T26019 | R59949 | R-59949,R 59949 | Others , PKC |
R59949 is used as a Diacylglycerol kinase (DGK) inhibitor. | |||
T19350 | H-Val-Ala-OH | Valyl-alanine | Endogenous Metabolite |
H-Val-Ala-OH (Valyl-alanine) is a dipeptide formed from L-Valine and L-Alanine residues. It has a role as a metabolite. H-Val-Ala-OH is a dipeptide formed from L-Valine and L-Alanine residues. | |||
T7507 | γ-L-Glutamyl-L-alanine | Others , Endogenous Metabolite | |
γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is the substrate of CRF21 (gamma-Glutamylcyclotransferase, GGCT). | |||
T13019 | Succinyl phosphonate trisodium salt | Dehydrogenase , Reactive Oxygen Species , Endogenous Metabolite | |
Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC) | |||
T10038 | 11-cis-Vaccenyl acetate | (Z)-Octadec-11-enyl acetate | Endogenous Metabolite |
11-cis-Vaccenyl acetate ((Z)-Octadec-11-enyl acetate) activates olfactory neurons located in the T1 sensilla on the antenna and mediates aggregation behavior in both male and female flies. | |||
T8403 | Cinacalcet | AMG 073 | CaSR |
Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease . | |||
T41286 | N6-Isopentenyladenosine | Endogenous Metabolite , Autophagy | |
N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different... | |||
T10760 | Ceramides Mixture | Telomerase | |
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ... | |||
T20533 | NNK | Nicotine-derived nitrosamine ketone | Lipoxygenase |
NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor. | |||
T9597 | H2S Donor 5a | Endogenous Metabolite | |
H2S Donor 5a is a H2S donor that could mimic the slow and continuous H(2)S generation process. | |||
T19456 | N-Glycolylneuraminic acid | NeuGc,GcNeu | Influenza Virus , Endogenous Metabolite |
N-Glycolylneuraminic acid (GcNeu) is a nonhuman sialic acid molecule synthesized in pigs. N-Glycolylneuraminic acid is a receptor of human and animal IAVs. | |||
T22967 | MEDICA16 | MEDICA 16 | GPR , Others , ATP Citrate Lyase |
Free fatty acid 1 (FFA1/GPR40) receptor agonist | |||
T15047 | Dacisteine | N,S-Diacetyl-L-cysteine | Others |
Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM). | |||
T20062 | Thiamine disulfide | TDS,Daiomin,Algoneurina | HIV Protease , Endogenous Metabolite |
Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication. Thiamine also acts as a cofactor for many centrally metabolizing... | |||
T7717 | Sodium 2-oxopropanoate | Sodium pyruvate | Reactive Oxygen Species , Endogenous Metabolite |
Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease. | |||
T40729 | D-Threonine | H-D-Thr-OH,D-Threonine | Endogenous Metabolite |
D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae. | |||
T12148 | N-Desmethyltamoxifen hydrochloride | Estrogen Receptor/ERR , Endogenous Metabolite , PKC | |
N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans. | |||
T12306 | OMDM-5 | Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM). | |||
T0260 | Meclofenamic acid sodium | Meclofenamate Sodium,Movens,Meclomen,Meclonax | Gap Junction Protein , COX |
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis. | |||
T11511 | Guanosine-5'-triphosphate disodium salt | 5'-GTP disodium salt | Others , Endogenous Metabolite |
Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and an energy source for translation and other important cellular processes. | |||
T7511 | Cyclo(his-pro) | NF-κB , Endogenous Metabolite | |
Cyclo(his-pro) is an endogenous cyclic dipeptide that exerts oxidative damage protection by selectively activating the transcription factor Nrf2 signalling pathway. | |||
T6588 | Mitoxantrone | mitozantrone | Topoisomerase , PKC |
Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisome... | |||
T5589 | H-Gly-Pro-OH | Glycyl proline,Glycyl-L-proline | Endogenous Metabolite |
H-Gly-Pro-OH (Glycyl proline) is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism | |||
T23204 | PSN 375963 | PSN 375963 hydrochloride | GPR |
PSN 375963 (PSN 375963 hydrochloride) hydrochloride is a synthetic agonist of the endogenous ligand for GPR119. | |||
T0601 | Monobenzyl phthalate | Phthalic Acid Monobenzyl Ester | Others , Endogenous Metabolite |
Monobenzyl phthalate (Phthalic Acid Monobenzyl Ester) is Phthalate metabolite. | |||
T1617 | Enrofloxacin | BAY-Vp2674,PD160788 | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry. | |||
T7173 | [Leu5]-Enkephalin | Leucine enkephalin,Leucyl-enkephalin,Leu-enkephalin | Opioid Receptor , Endogenous Metabolite |
[Leu5]-Enkephalin (Leu-enkephalin) is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM, respectively) | |||
T2334 | Avanafil | TA1790 | PDE |
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction. | |||
T19147 | 5-ALA benzyl ester hydrochloride | Benzyl-ALA hydrochloride | Others , Endogenous Metabolite |
5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor. 5-ALA benzyl ester hydrochloride is used as a photodetection agent. 5-ALA benzyl ester hydrochloride could induce protoporphyrin ... | |||
T3213 | Hematoporphyrin dihydrochloride | Hematoporphyrin IX dihydrochloride | Apoptosis , Others , Endogenous Metabolite |
Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) is a substrate for affinity chromatography of heme-binding proteins. | |||
TP1158 | Copper tripeptide | GHK-Cu | Others , Endogenous Metabolite |
Copper tripeptide (GHK-Cu) is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T12287 | Octadecanedioic acid | Endogenous Metabolite | |
Octadecanedioic acid is an endogenous metabolite, is a long-chain dicarboxylic acid. | |||
TN1490 | Chrysoeriol | ERK , p38 MAPK , Akt | |
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect. | |||
T15720 | Lathosterol | Endogenous Metabolite | |
Lathosterol, a molecule akin to cholesterol, serves as a biomarker for the body's total cholesterol synthesis, as indicated by its serum concentration. | |||
T4799 | Indole | Others , Endogenous Metabolite | |
Indole has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. It can be produced by bacteria as a degradation product of the amino acid tryptophan. ... | |||
T13719 | Hexadecanal | Palmitaldehyde | Endogenous Metabolite |
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals. | |||
T0069 | Uracil | Others , Endogenous Metabolite | |
Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synt... | |||
T8165 | Erythrodiol | Endogenous Metabolite , ABC | |
Erythrodiol, an olive oil component, promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. | |||
T20446 | Creosol | Endogenous Metabolite | |
Creosol is an agent of Antioxidant and Antibacterial. | |||
T5665 | Geraniol | Others , Endogenous Metabolite , Antifungal | |
geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress. | |||
T0647 | Tryptamine | Dehydrogenase , 5-HT Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
Tryptamine is a monoamine alkaloid found in animals, plants, and fungi. It contains an indole ring structure and is structurally analogous to the tryptophan. It is found in trace amounts in the brains of mammals and is r... | |||
T8272 | Trierucin | Others , Endogenous Metabolite | |
Trierucin is a trierucic acid triglyceride isolated from the seed oil. | |||
T0586 | Lactose | Others , Endogenous Metabolite | |
Lactose is a disaccharide derived from galactose and glucose that is found in milk. | |||
T36790 | (Ethoxymethyl)benzene | Endogenous Metabolite | |
(Ethoxymethyl)benzene is an endogenous metabolite. | |||
T5352 | GLYCODEOXYCHOLIC ACID | Others , Endogenous Metabolite | |
Glycodeoxycholic Acid is a bile acid that induces severe pancreatitis in rats. It can induce the apoptosis of SMMC-7721 cells. | |||
T8031 | Terephthalic acid | Others , Endogenous Metabolite | |
Terephthalic acid, an isomer of the three phthalic acids, serves as a precursor to the polyester PET, which is utilized in manufacturing plastic bottles and clothing. | |||
T7602 | Theaflavin | Influenza Virus , Endogenous Metabolite | |
Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antioxidant, anticancer, anti-inflammatory, and antiviral properties | |||
T8086 | Decyl aldehyde | Others , Endogenous Metabolite | |
Decyl aldehyde is a ten-carbon aldehyde that is a substrate for bacterial luciferase. | |||
T4809 | Pyrimidine | Metadiazine | Others , Endogenous Metabolite |
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ... | |||
T37508 | Meconin | Endogenous Metabolite | |
Meconin, a noscapine metabolite, is a urinary detection marker for illicit opiate misuse. This product is intended for use as a forensic standard. | |||
TN6833 | Octanal | Endogenous Metabolite , Antibacterial | |
octanal is a natural product with antioxidant and antimicrobial activities. | |||
T37501 | Ethoxyacetic acid | Endogenous Metabolite | |
Ethoxyacetic acid is an endogenous metabolite of ethylene glycol monoethyl ether acetate. | |||
T4776 | Glycerol | Glycerin | Endogenous Metabolite |
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol... | |||
T8049 | Pentadecanoic acid | Others , Endogenous Metabolite | |
Pentadecylic acid is a saturated fatty acid. | |||
T4794 | Glutaric acid | Endogenous Metabolite | |
Glutaric acid is a simple five-carbon linear dicarboxylic acid. Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan | |||
T2228 | Adipic acid | Others , Endogenous Metabolite | |
Adipic acid is a precursor for the production of nylon. | |||
T37298 | Spinacine | Endogenous Metabolite | |
Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotens... | |||
TN6752 | Dimethyl sulfone | Endogenous Metabolite | |
Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ... | |||
T5737 | Euphol | Others , Lipase , Endogenous Metabolite | |
Euphol, an alcohol tetracyclic triterpene, has a wide range of pharmacological properties and is considered to have anti-inflammatory action. | |||
T4761 | Pyridoxal hydrochloride | Others , Endogenous Metabolite | |
The 4-carboxyaldehyde form of vitamin B6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. | |||
T5985 | Glycolic acid | Tyrosinase , Endogenous Metabolite | |
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation,and used in skincare products | |||
T13581 | Biotin sulfone | Endogenous Metabolite | |
Biotin sulfone is isolated as a natural metabolite of biotin. | |||
T19418 | Methionine sulfoxide | Endogenous Metabolite | |
Methionine sulfoxide, an oxidation product of methionine formed through interaction with reactive oxygen species, serves as a biomarker for oxidative stress in vivo. | |||
T5812 | Zinc Phytate | Others | |
Zinc Phytate, present in food, plays a crucial role in human nutrient absorption. | |||
T5565 | Undecanedioic acid | Others , Endogenous Metabolite | |
Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specifically with elastin. | |||
T5228 | Nicotinuric acid | Others , Endogenous Metabolite | |
Nicotinuric acid is an acyl glycine which is normally minor metabolites of fatty acids. Acyl glycines are produced through the action of glycine N-acyltransferase. | |||
T7331 | Ursocholic acid | Endogenous Metabolite | |
Ursocholic acid, a bile acid found predominantly in bile of mammals. | |||
T2724 | Caryophyllene oxide | Others , Endogenous Metabolite | |
Caryophyllene oxide is isolated from Aegle marmelos, with anti-inflammatory activity. | |||
T4883 | Creatine | Methylguanidoacetic acid | Endogenous Metabolite |
Creatine (Methylguanidoacetic acid) is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. Creati... | |||
T5074 | Cholesteryl palmitate | Others , Endogenous Metabolite | |
Cholesteryl palmitic acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a ... | |||
T8034 | Dimethyl Trisulfide | Others , Endogenous Metabolite | |
Dimethyl trisulfide is the simplest organic trisulfide found in garlic, onion, broccoli, and similar plants. Dimethyl trisulfide is a cyanide antidote. | |||
TQ0284 | Hydroxyphenyllactic acid | Endogenous Metabolite , Antifungal | |
Hydroxyphenyllactic acid is an antifungal metabolite, fungi such as Lactobacillus sp. SK007. | |||
T6060 | (±) Anabasine | Endogenous Metabolite | |
(±) Anabasine is a muscle relaxant that can be used for muscle relaxation during surgery. | |||
Fr13756 | Isonicotinic acid | Endogenous Metabolite , Drug Metabolite | |
Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biotransformation also to be catalyzed by cyt... | |||
T0965 | Histamine | Ergamine | 5-HT Receptor , Endogenous Metabolite , Histamine Receptor |
Histamine (Ergamine) is an amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting ne... | |||
T0853 | Adenosine | D-Adenosine,Adenine riboside | Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy |
Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities. | |||
T4729 | Phosphonoacetic acid | Endogenous Metabolite | |
Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is primarily located in the cytoplasm. Phosph... | |||
T4913 | Maleic acid | Endogenous Metabolite , Antibacterial | |
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of L. monocytogenes and E. coli. | |||
T36788 | 2-Methylacetophenone | Endogenous Metabolite | |
2-Methylacetophenone is a human endogenous metabolite. | |||
T36789 | 2-Methylcyclohexanone | Endogenous Metabolite | |
2-Methylcyclohexanone is a human endogenous metabolite. | |||
T7095 | Hexacosanoic acid | Cerotic acid | Endogenous Metabolite |
Hexacosanoic acid, a very long-chain fatty acid, is related to adrenoleukodystrophy (ALD), adrenomyeloneuropathy (AMN) and atherosclerosis. | |||
------------------------ More ------------------------ |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPK-01222 | APLN Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... | |||
TMPK-01221 | APLN Protein, Mouse, Recombinant (hFc & Avi), Biotinylated | Mouse | HEK293 Cells |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... | |||
TMPK-01236 | APLN Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized... | |||
TMPH-03271 | Complement factor D Protein, Rat, Recombinant (His & Myc) | Rat | HEK293 Cells |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classi... | |||
TMPH-03272 | Complement factor D Protein, Rat, Recombinant (His) | Rat | P. pastoris (Yeast) |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classi... | |||
TMPY-02062 | SULT1A1 Protein, Human, Recombinant (His) | Human | E. coli |
Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid... | |||
TMPH-01290 | ERVK-6 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous... | |||
TMPY-02128 | Serpin B1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healt... | |||
TMPH-02298 | Urocortin-3 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. | |||
TMPH-01289 | ERVK-6 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous... | |||
TMPH-02682 | GSTM3 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GSTM3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc t... | |||
TMPH-02683 | GSTP1 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ... | |||
TMPY-04121 | NAGA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
NAGA (Alpha-N-Acetylgalactosaminidase) is a Protein Coding gene. NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. It belongs to ... | |||
TMPH-03138 | GST Protein, Plasmodium falciparum, Recombinant (His) | Plasmodium falciparum | P. pastoris (Yeast) |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin). GST Protein,... | |||
TMPY-04934 | Serpin A3n Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Serpina3n may represent a circulating biomarker of muscle atrophy associated with GC and, broadly, a reflection of dynamic changes in muscle mass. Serpina3n blocks endogenous increases in the activity of select skeletal ... | |||
TMPH-03483 | Saxiphilin Protein, Aquarana catesbeiana, Recombinant (His) | Lithobates catesbeiana | HEK293 Cells |
Binds specifically to the neurotoxin saxitoxin. Its physiological role may be to transport or sequester an endogenous organic molecule other than Fe(3+). It may participate in a detoxification mechanism for neutralizing ... | |||
TMPH-01424 | GUCA2B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and el... | |||
TMPH-01291 | ERVK-7 Protein, Human, Recombinant (His) | Human | E. coli |
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.; SU mediates re... | |||
TMPH-03310 | GUCY2C Protein, Rat, Recombinant (His & Myc) | Rat | HEK293 Cells |
Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptide guanylin. GUCY2C Protein, Rat... | |||
TMPH-02163 | Syncytin-1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through ... | |||
TMPH-01595 | KMO Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA r... | |||
TMPH-03166 | Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) | Pseudomonas aeruginosa | E. coli |
Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD)... | |||
TMPH-01298 | EPHX1 Protein, Human, Recombinant (His) | Human | E. coli |
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lip... | |||
TMPK-01162 | NTS1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Crystal structures of neurotensin receptor subtype 1 (NTS1) allowed us to visualize the binding mode of the endogenous peptide hormone neurotensin and its pharmacologically active C-terminal fragment NT(8-13) within the ... | |||
TMPK-00982 | NTS1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Crystal structures of neurotensin receptor subtype 1 (NTS1) allowed us to visualize the binding mode of the endogenous peptide hormone neurotensin and its pharmacologically active C-terminal fragment NT(8-13) within the ... | |||
TMPH-01399 | GSTP1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ... | |||
TMPH-01398 | GSTP1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). ... | |||
TMPK-00592 | Latexin Protein, Human, Recombinant (His) | Human | E. coli |
Latexin, the endogenous protein inhibitor of the A/B subfamily of metallocarboxypeptidases, is expressed in small nociceptive neurons in sensory ganglia and in a subset of neurons in the telencephalon. Recently, the late... | |||
TMPJ-00816 | FBPase1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein whic... | |||
TMPH-01325 | FAAH2 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatt... | |||
TMPY-01771 | Latexin Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly express... | |||
TMPH-02438 | IL-1 alpha/IL1A Protein, Rhesus macaque, Recombinant (His & SUMO) | Rhesus | E. coli |
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammat... | |||
TMPH-00864 | RO60 Protein, Human, Recombinant (His) | Human | E. coli |
RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation. Binds to endogeno... | |||
TMPK-01158 | Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulat... | |||
TMPJ-00473 | QPRTase Protein, Human, Recombinant (His) | Human | E. coli |
Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves ... | |||
TMPJ-00963 | CDKN2C Protein, Human, Recombinant (His) | Human | E. coli |
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in... | |||
TMPH-02648 | PKDCC Protein, Mouse, Recombinant (His & Myc) | Mouse | Baculovirus Insect Cells |
Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylati... | |||
TMPJ-01392 | IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His) | Cavia porcellus | E. coli |
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and per... | |||
TMPY-03172 | Argininosuccinate lyase Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established r... | |||
TMPY-02264 | LRIG1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a tumor suppressor and a negative regulator of several receptor tyrosine kinases. Leucine-rich repeats and immunoglobulin-like domains containing protein ... | |||
TMPY-00561 | Neurotensin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
NTS (Neurotensin) is a Protein Coding gene. This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. NTS is a neuropeptide distributed in the central nervous and digestive systems. It belongs ... | |||
TMPJ-00314 | ACVR2B Protein, Human, Recombinant (hFc & His) | Human | HEK293 Cells |
Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors... | |||
TMPY-01842 | Neuroligin-3/NLGN3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Neuroligin 3 (NLGN3) is a member of the type-B carboxylesterase/lipase family. Neuroligins (NLGNs) are a family of presumptive postsynaptic cell adhesion molecules. Neuroligins (NLs) constitute a family of cell-surface p... | |||
TMPJ-00526 | Langerin/CD207 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family. Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the e... | |||
TMPY-02885 | CD1B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD1B contains 1 Ig-like (immunoglobulin-like) domain and belongs to the CD1 family. CD1 family members are transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) protein... | |||
TMPY-02402 | WTAP Protein, Human, Recombinant (GST) | Human | E. coli |
Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identif... | |||
TMPY-01635 | PCSK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the... | |||
TMPJ-00681 | EDIL3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
EGF-Like Repeat and Discoidin I-Like Domain-Containing Protein 3 (EDIL3) is a 52 kDa extracellular matrix protein that is expressed by endothelial tissues during embryonic vascular development. EDIL3 becomes quiescent at... | |||
TMPY-02689 | MMP-3 Protein, Human, Recombinant | Human | E. coli |
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular... | |||
TMPJ-00948 | Endostatin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑termi... | |||
------------------------ More ------------------------ |
カタログ番号 | 製品名 | ||
---|---|---|---|
L2500 | Human Endogenous Metabolite Library | 499 compounds | |
A collection of 499 selected human endogenous metabolites for high throughput and high content screening. | |||
L2501 | Human Endogenous Metabolite Compound Library Plus | 1283 compounds | |
L2570 | Human Metabolite Library | 4454 compounds | |
A unique collection of 4454 human metabolites for high-throughput, high-content screening. | |||
L2700 | Adrenergic Receptor-Targeted Compound Library | 193 compounds | |
A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; | |||
L1580 | GPCR Compound Library Plus | 338 compounds | |
Well-chosen 338 GPCR targeting compounds with unique structures; | |||
L1500 | GPCR Compound Library | 1940 compounds | |
A unique collection of 1940 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; | |||
L2550 | Glutamine Metabolism Compound Library | 565 compounds | |
A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ... |