store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 20,500 | |||
5 mg | 在庫あり | ¥ 61,000 | |||
10 mg | 在庫あり | ¥ 90,500 | |||
25 mg | 在庫あり | お問い合わせ | |||
50 mg | 在庫あり | お問い合わせ |
説明 | 740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K. |
In vitro | 740 Y-P is a synthetic biotinylated peptide. 740 Y-P stimulates mitogenesis at the lowest concentration tested (1 mg/mL). The peptide stimulates mitogenesis in both the presence and absence of serum (0.5%) and in the former instance, a maximal response observed at 50 mg/mL. 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell-permeable SH2 domain-binding peptide [1]. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose-dependent and does not require insulin[2]. |
別名 | 740YPDGFR, PDGFR 740Y-P |
分子量 | 3270.7 |
分子式 | C141H222N43O39PS3 |
CAS No. | 1236188-16-1 |
store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 15 mg/mL (4.58 mM)
You can also refer to dose conversion for different animals. 詳細
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740 Y-P 1236188-16-1 Autophagy PI3K/Akt/mTOR signaling PI3K VSMC inhibit alzheimer’s disease aortic p85 binding SH2 740YPDGFR 740 Y P cancer 740 YP PDGFR 740Y-P peptide Inhibitor thoracic Phosphoinositide 3-kinase inhibitor