Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AI-10-47 (1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47) is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM).
説明 | AI-10-47 (1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47) is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM). |
ターゲット&IC50 | CBFβ-RUNX binding:3.2 μM |
In vitro | AI-10-47 significantly inhibits ME-1, TUR, M0-91, THP-1 and U937 cell growt;AI-10-47 with 10 μM weakly inhibits CBFβ-RUNX binding. |
別名 | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47 |
分子量 | 279.22 |
分子式 | C13H8F3N3O |
CAS No. | 1256094-31-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (358.14 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AI-10-47 1256094-31-1 Others inhibit leukemia CBFβ U937 AI1047 RUNX 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47 Inhibitor M0-91 ME-1 THP-1 TUR AI 10 47 cell inhibitor