Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約10-14 週間 | ¥ 590,000 |
50 mg | 約10-14 週間 | ¥ 776,000 |
100 mg | 約10-14 週間 | ¥ 1,056,000 |
説明 | AKT-IN-3 is a potent, orally active low hERG blocking Akt inhibitor (IC50: 1.4 nM, 1.2 nM, and 1.7 nM for Akt1, Akt2, and Akt3). AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. |
ターゲット&IC50 | Akt3:1.7 nM, p70 S6K:8.9, PKA:0.3 nM, Akt2:1.2 nM, Akt1:1.4 nM |
分子量 | 526.36 |
分子式 | C23H23Cl2F2N5O3 |
CAS No. | 2374740-21-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AKT-IN-3 2374740-21-1 Cytoskeletal Signaling PI3K/Akt/mTOR signaling Akt AKT IN 3 AKTIN3 Inhibitor inhibitor inhibit