Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AS057278 (3-Methylpyrazole-5-carboxylic acid) is an D-amino acid oxidase (DAAO) inhibitor.
説明 | AS057278 (3-Methylpyrazole-5-carboxylic acid) is an D-amino acid oxidase (DAAO) inhibitor. |
In vivo | AS057278 was able to normalize phencyclidine (PCP)-induced prepulse inhibition after acute (80 mg/kg) and chronic (20 mg/kg b.i.d.) oral administration in mice.?AS057278 after oral chronic treatment (10 mg/kg b.i.d.) was able to normalize PCP-induced hyperlocomotion.?AS057278 has the potential to anti-psychotic action toward both cognitive and positive symptoms of schizophrenia[1]. |
別名 | 3-Methylpyrazole-5-carboxylic acid |
分子量 | 126.11 |
分子式 | C5H6N2O2 |
CAS No. | 402-61-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25mg/mL(198.24mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AS057278 402-61-9 Others Prepulse inhibition AS 057278 AS-057278 Inhibitor Non-peptidic D-amino acid oxidase inhibit Schizophrenia 3-Methylpyrazole-5-carboxylic acid Orally active BBB penetrant inhibitor