Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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2 mg | 在庫あり | ¥ 9,000 | |||
5 mg | 在庫あり | ¥ 14,000 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 56,000 | |||
50 mg | 在庫あり | ¥ 98,500 | |||
100 mg | 在庫あり | ¥ 146,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 18,000 |
説明 | AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM). |
ターゲット&IC50 | PAR2:23 nM(kd) |
In vitro | AZ3451 is selective for PAR2 over PAR4 and PAR1 (IC50s = <2.5, 380, and >50,000 nM, respectively, in a β-arrestin-2 recruitment assay). AZ3541 completely inhibits SLIGRL-induced phosphorylation of ERK in 1321N1 astrocytoma cells when used at a concentration of 10 μM. |
分子量 | 571.46 |
分子式 | C30H27BrN4O3 |
CAS No. | 2100284-59-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
DMSO: 80 mg/mL (140 mM)
You can also refer to dose conversion for different animals. 詳細
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AZ3451 2100284-59-9 GPCR/G Protein Protease-activated Receptor inhibit Protease Activated Receptor (PAR) AZ-3451 AZ 3451 Thrombin receptors Inhibitor inhibitor