Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 67,500 |
5 mg | 在庫あり | ¥ 169,000 |
10 mg | 在庫あり | ¥ 226,500 |
25 mg | 在庫あり | ¥ 355,000 |
50 mg | 在庫あり | ¥ 454,500 |
100 mg | 在庫あり | ¥ 638,000 |
説明 | AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC). |
ターゲット&IC50 | EG5:2 nM |
別名 | AZD4877 |
分子量 | 503.66 |
分子式 | C28H33N5O2S |
CAS No. | 758722-49-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (109.2 mM)
You can also refer to dose conversion for different animals. 詳細
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AZD-4877 758722-49-5 Apoptosis Cytoskeletal Signaling Kinesin AZD4877 AZD 4877 Inhibitor inhibitor inhibit