Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 16,000 |
5 mg | 在庫あり | ¥ 37,000 |
10 mg | 在庫あり | ¥ 54,000 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 57,500 |
説明 | Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property. |
In vitro | Chemical characterization studies revealed the major active constituents of the herb as the triterpenoid saponins, bacosides. Bacoside A, the vital neuroprotective constituent, is composed of four constituents viz., bacoside A3, bacopaside II, jujubogenin isomer of Bacopasaponin C (bacopaside X) and Bacopasaponin C. B. monnieri extracts as well as bacosides successfully establish a healthy antioxidant environment in various tissues especially in liver and brain. Free radical scavenging, suppression of lipid peroxidation and activation of antioxidant enzymes by bacosides help to attain a physiological state of minimized oxidative stress. The molecular basis of neuroprotective activity of bacosides is attributed to the regulation of mRNA translation and surface expression of neuroreceptors such as AMPAR, NMDAR and GABAR in the various parts of the brain. Bioavailability as well as binding of neuroprotective agents (such as bacosides) to these receptors is controlled by the Blood Brain Barrier (BBB). However, nano conversion of these drug candidates easily resolves the BBB restriction and carries a promising role in future therapies[1] |
植物由来 |
分子量 | 899.07 |
分子式 | C46H74O17 |
CAS No. | 178064-13-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (66.73 mM)
You can also refer to dose conversion for different animals. 詳細
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Bacopasaponin C 178064-13-6 Membrane transporter/Ion channel Microbiology/Virology Neuroscience NMDAR GABA Receptor Anti-infection Inhibitor Parasite inhibit inhibitor