keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
説明 | Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment. |
In vitro | Bax inhibitor peptide V5 (BIP-V5; 0-50 μM) decreases cell death in STF-cMyc cells but not in SW620 or NCI-H23 cells.[1]. V5 treatment upregulates expression of anti-apoptotic proteins Bcl-2 and XIAP by more than 3- and 11-fold and downregulates expression of apoptosis-inducing proteins Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively[2]. |
In vivo | Bax inhibitor peptide V5 (BIP-V5; 100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model[2]. |
別名 | Bax inhibitor peptide V5 acetate(579492-81-2 free base) |
分子量 | 646.85 |
分子式 | C29H54N6O8S |
CAS No. | T10463L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 100 mg/mL (170.42 mM), Sonication is recommended.
DMSO: 100 mg/mL (170.42 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Bax inhibitor peptide V5 acetate T10463L Apoptosis 579492-81-2 free base Bax inhibitor peptide V5 Acetate Bax inhibitor peptide V5 acetate(579492-81-2 free base) Bax inhibitor peptide V-5 acetate 579492-81-2 Inhibitor inhibitor inhibit