Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bimosiamose disodium has anti-inflammatory effects[1]. Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s of 88 μM, 20 μM, and 86 μM for E-selectin, P-selectin, and L-selectin, respectively.
ターゲット&IC50 | L-selectin:86 μM, P-selectin:20 μM, Eselectin:88 μM |
In vitro | Bimosiamose (TBC-1269) effectively inhibits neutrophil recruitment to inflammation sites by obstructing the initial rolling phase of recruitment, without exerting cytotoxic effects on neutrophils[1]. This action prevents cell recruitment, emphasizing its role in controlling the inflammatory response without harming these immune cells. |
別名 | TBC-1269Z |
分子量 | 908.902 |
分子式 | C46H54Na2O16 |
CAS No. | 187269-60-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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Bimosiamose disodium 187269-60-9 Cytoskeletal Signaling Integrin TBC-1269Z Bimosiamose Inhibitor inhibitor inhibit