Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR with IC50 of 1.3 nM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 12,000 | |||
2 mg | 在庫あり | ¥ 17,000 | |||
5 mg | 在庫あり | ¥ 28,000 | |||
10 mg | 在庫あり | ¥ 45,500 | |||
25 mg | 在庫あり | ¥ 99,500 | |||
50 mg | 在庫あり | ¥ 151,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 30,500 |
説明 | Broflanilide is metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin GABA receptor and inhibits S. litura RDL GABAR with IC50 of 1.3 nM. |
ターゲット&IC50 | GlyR α1 (A288Gβ):0.706 μM, GlyR α1 (A288G):0.149 μM, GABA receptor:1.3 nM(S. litura RDL), GABAA α1β3γ2:3 μM(mammalian), GlyR:3 μM(human) |
In vitro | Broflanilide is an insecticide and metabolized to desmethyl-broflanilide. Desmethyl-broflanilide shows weak activity against human GABAA α1β2γ2 receptor, the mammalian GABAA α1β3γ2 receptor and human glycine receptor (GlyR) α1β with IC50s >3 μM, and less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G with IC50s of 0.706 and 0.149 μM respectively. |
分子量 | 663.28 |
分子式 | C25H14BrF11N2O2 |
CAS No. | 1207727-04-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225 mg/mL (339.22 mM)
You can also refer to dose conversion for different animals. 詳細
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Broflanilide 1207727-04-5 Membrane transporter/Ion channel Neuroscience GABA Receptor inhibit Gamma-aminobutyric acid Receptor γ-Aminobutyric acid Receptor Inhibitor inhibitor