Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 104,000 |
5 mg | 在庫あり | ¥ 209,500 |
10 mg | 在庫あり | ¥ 303,000 |
25 mg | 在庫あり | ¥ 480,000 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 273,500 |
説明 | C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300. |
In vitro | C-82 inhibits the activation of isolated primary mouse quiescent hepatic stellate cells (HSCs) and promotes cell death in culture-activated HSCs. |
In vivo | PRI-724 is phosphorylated-C-82 and is rapidly hydrolyzed to its active form C-82 in vivo, and pre-clinical studies have shown a very acceptable toxicity profile. |
分子量 | 578.66 |
分子式 | C33H34N6O4 |
CAS No. | 1422253-37-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (95.05 mM)
You can also refer to dose conversion for different animals. 詳細
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C-82 1422253-37-9 Chromatin/Epigenetic Cytoskeletal Signaling Stem Cells Epigenetic Reader Domain Wnt/beta-catenin C 82 C82 Inhibitor inhibitor inhibit