Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBRM1-BD2-IN-8 (compound 34) is a potent PBRM1 Bromodomain inhibitor (PBRM1-BD2 Kd=4.4 μM, PBRM1-BD2 IC50=0.16 μM; PBRM1-BD5 Kd=25 μM). PBRM1-BD2-IN-8 shows anti-cancer activity.
説明 | PBRM1-BD2-IN-8 (compound 34) is a potent PBRM1 Bromodomain inhibitor (PBRM1-BD2 Kd=4.4 μM, PBRM1-BD2 IC50=0.16 μM; PBRM1-BD5 Kd=25 μM). PBRM1-BD2-IN-8 shows anti-cancer activity. |
In vitro | PBRM1-BD2-IN-8 (0-100 μM; 48 h) inhibits the growth of PBRM1-dependent prostate cancer cells[1]. |
分子量 | 317.18 |
分子式 | C15H13BrN2O |
CAS No. | 2819989-75-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (173.4 mM)
You can also refer to dose conversion for different animals. 詳細
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PBRM1-BD2-IN-8 2819989-75-6 Chromatin/Epigenetic Epigenetic Reader Domain PBRM1BD2IN8 Inhibitor inhibitor inhibit