keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 31,500 | |||
5 mg | 在庫あり | ¥ 128,000 | |||
10 mg | 在庫あり | ¥ 180,000 | |||
25 mg | 在庫あり | ¥ 280,000 | |||
50 mg | 在庫あり | ¥ 379,000 | |||
100 mg | 在庫あり | ¥ 512,000 |
説明 | CALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. |
In vitro | CALP3 inhibits glutamate caused a large sustained increase in [Ca2+]i in a dose-dependent manner (IC50=37.25 μM) in Fura-2-loaded neuronal cultures. CALP3 inhibits glutamate-induced cytotoxicity in a dose-dependent manner (IC50=50.97 μM) in cultured rat neocortical neurons. CALP3 causes dose-dependent inhibition of apoptosis (IC50=33.41 μM). CALP3 (100 μM) inhibits apoptosis induced by HIV gp120 and SAg in Human T cells. CALP3 (100?μM; 15?min pretreatment) reduces gossypol-induced necrosis and increases the fraction of live cells[1][2]. |
分子量 | 941.12 |
分子式 | C46H72N10O11 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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CALP3 acetate(261969-05-5 free base) Membrane transporter/Ion channel Metabolism Calcium Channel CALP-3 acetate(261969-05-5 free base) CALP3 acetate(261969055 free base) CALP3 acetate(261969 05 5 free base) Inhibitor inhibitor inhibit