store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cassiaside is a naphthyl ketone glycoside that inhibits BACE1 (IC50= 4.45 μM; Ki=9.85 μM).Cassiaside exhibits significant hepatoprotective effects against galactosamine injury and has potential anti-Alzheimer's disease (AD) activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 19,500 | |||
5 mg | 在庫あり | ¥ 49,000 | |||
10 mg | 在庫あり | ¥ 85,000 | |||
25 mg | 在庫あり | ¥ 141,500 | |||
50 mg | 在庫あり | お問い合わせ |
説明 | Cassiaside is a naphthyl ketone glycoside that inhibits BACE1 (IC50= 4.45 μM; Ki=9.85 μM).Cassiaside exhibits significant hepatoprotective effects against galactosamine injury and has potential anti-Alzheimer's disease (AD) activity. |
ターゲット&IC50 | BACE1:4.45 μM, BACE1:9.85 μM(Ki) |
In vitro | The numbers of revertants per plate decreased significantly when this extract was added to the assay system using Salmonella typhimurium TA100 and/or TA98. The MeOH extract was then sequentially partitioned with CH2Cl2, n-BuOH and H2O. The CH2Cl2 and n-BuOH fractions possessed antimutagenic activity but the H2O fraction was inactive. Neither the MeOH extract nor its fractions were capable of inhibiting the direct-acting mutagen N-methyl-N'-nitro-N-nitrosoguanidine suggesting that these fractions may prevent the metabolic activation of AFB1 or scavenge the electrophilic intermediate capable of inducing mutations[1] |
分子量 | 420.37 |
分子式 | C20H20O10 |
CAS No. | 13709-03-0 |
store at low temperature,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (47.57 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Cassiaside 13709-03-0 Neuroscience Beta-Secretase BACE Inhibitor inhibitor inhibit