Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 10,000 | |||
100 mg | 在庫あり | ¥ 13,500 | |||
200 mg | 在庫あり | ¥ 21,500 | |||
500 mg | お問い合わせ | ¥ 36,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 15,000 |
説明 | Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep. |
ターゲット&IC50 | 3-phosphoglycorate:0.29 mM(ki), ATP:0.29 mM(ki) |
In vitro | In sheep and calves, a single administration of Clorsulon (15 mg/kg) effectively induces damage to the cortical and intestinal tissues of the liver flukes, thereby expelling immature liver flukes from the host organism. |
In vivo | Clorsulon is a competitive inhibitor (Ki=0.29 mM) of both 3-phosphoglycerate and ATP, capable of suppressing glucose utilization and the formation of acetate and propionate. |
別名 | L631529, MK401 |
分子量 | 380.66 |
分子式 | C8H8Cl3N3O4S2 |
CAS No. | 60200-06-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 7 mg/mL (18.38 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 71 mg/mL (186.5 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Clorsulon 60200-06-8 Membrane transporter/Ion channel Microbiology/Virology ATPase Antibiotic Parasite Fasciola 3-phosphoglycorate Inhibitor glucose utilization L 631529 gigantica L631529 L-631529 MK401 MK 401 MK-401 inhibit Flukicidal inhibitor