Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.
説明 | Delpazolid (LCB01-0371), also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus. |
ターゲット&IC50 | MSSA:2 μg/mL (MIC90), MRSA:2 μg/mL (MIC90) |
別名 | LCB01-0371 |
分子量 | 308.31 |
分子式 | C14H17FN4O3 |
CAS No. | 1219707-39-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (97.30 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. 詳細
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Delpazolid 1219707-39-7 Microbiology/Virology Antibacterial Antibiotic inhibit Bacterial LCB01-0371 Inhibitor inhibitor