Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Demethylisoencecalin (6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran) has anti-hyperglycemic activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 25,000 | |||
5 mg | 在庫あり | ¥ 61,500 | |||
10 mg | 在庫あり | ¥ 90,000 | |||
25 mg | 在庫あり | ¥ 153,500 | |||
50 mg | 在庫あり | ¥ 218,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 64,500 |
説明 | Demethylisoencecalin (6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran) has anti-hyperglycemic activity. |
In vitro | Demethylisoencecalin (1) and caleins A (4) and C (5) (3.16–31.6 mg/kg, p.o.), the major components from an infusion of Calea ternifolia controlled postprandial glucose levels during an oral sucrose tolerance test (OSTT, 3 g/kg) in normal and nicotinamide/streptozotocin (NA/STZ, 40/100 mg/kg) hyperglicemic mice. The effects were comparable to those of acarbose (5 mg/kg). During the isolation of 1, 4, and 5, four additional metabolites not previously reported for the plant, were obtained, namely 6-acetyl-5-hydroxy-2-methyl-2-hydroxymethyl-2H-chromene (3), herniarin (6), scoparone (7), and 4′,7-dimethylapigenin (8). In addition, the structure of calein C (5) was confirmed by X-ray analysis. Pharmacological evaluation of the essential oil of the species (31.6–316.2 mg/kg, p.o.) provoked also an important decrement of blood glucose levels during an OSTT[1]. |
別名 | 6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran |
分子量 | 218.25 |
分子式 | C13H14O3 |
CAS No. | 24672-84-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (274.91 mM)
You can also refer to dose conversion for different animals. 詳細
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Demethylisoencecalin 24672-84-2 Others 6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran Inhibitor inhibitor inhibit