Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 63,500 |
5 mg | 在庫あり | ¥ 158,000 |
10 mg | 在庫あり | ¥ 248,000 |
25 mg | 在庫あり | ¥ 365,000 |
50 mg | 在庫あり | ¥ 498,000 |
100 mg | 在庫あり | ¥ 670,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 180,500 |
説明 | ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor. |
In vitro | ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12nM and 656 nM for PS1and PS2, respectively[1]. |
In vivo | Brain levels of ELN318463 (30 mg/kg) are 0.754 μM in FVB brains and 0.69 μM, and of ELN318463(100 mg/kg) are 2.7 μM in FVB brains and 1.87 μM in PDAPP brains[1]. |
別名 | ELN318463 (racemate), ELN 318463 racemate |
分子量 | 471.8 |
分子式 | C19H20BrClN2O3S |
CAS No. | 851599-82-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (105.98 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ELN318463 racemate 851599-82-1 Neuroscience Proteases/Proteasome Stem Cells Gamma-secretase ELN318463 ELN 318463 ELN318463 (racemate) racemate ELN-318463 ELN 318463 racemate Inhibitor inhibitor inhibit