Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 75,500 |
5 mg | 在庫あり | ¥ 183,500 |
10 mg | 在庫あり | ¥ 250,500 |
25 mg | 在庫あり | ¥ 379,000 |
50 mg | 在庫あり | ¥ 512,000 |
100 mg | 在庫あり | ¥ 672,500 |
説明 | FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells. |
In vivo | In male C57BL/6 mice with B16-F10 xenografts, FR-167356 (200 mg/kg) reduces bone metastasis, inhibits tumor growth, and reduces the expression of MMP9[1]. |
別名 | FR167356, FR 167356 |
分子量 | 378.25 |
分子式 | C19H17Cl2NO3 |
CAS No. | 174185-16-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (7.08 mM)
You can also refer to dose conversion for different animals. 詳細
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FR-167356 174185-16-1 Membrane transporter/Ion channel ATPase FR167356 FR 167356 Inhibitor inhibitor inhibit