Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FTBMT is a selective GPR52 agonist (EC50: 75 nM) and it also has antipsychotic and procognitive properties.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 11,500 | |||
5 mg | 在庫あり | ¥ 20,000 | |||
10 mg | 在庫あり | ¥ 34,000 | |||
25 mg | 在庫あり | ¥ 75,500 | |||
50 mg | 在庫あり | ¥ 133,500 | |||
100 mg | 在庫あり | ¥ 190,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 21,500 |
説明 | FTBMT is a selective GPR52 agonist (EC50: 75 nM) and it also has antipsychotic and procognitive properties. |
ターゲット&IC50 | GPR52:75 nM(EC50) |
In vitro | In CHO cells expressing human, mouse, or rat GPR52, FTBMT (0.1-10 μM) improves intracellular cAMP levels (pEC50s of 7.03, 6.85, and 6.87, respectively)[2]. |
In vivo | In rats, FTBMT (3 or 10 mg/kg, 48 hours) improves recognition and spatial working memory. FTBMT (30 mg/kg, 90 minutes) shows antipsychotic-like activity without causing catalepsy in mice[2] |
分子量 | 392.35 |
分子式 | C19H16F4N4O |
CAS No. | 1358575-02-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (114.69 mM), Sonication is recommended.
H2O: < 0.1 mg/mL (insoluble)
You can also refer to dose conversion for different animals. 詳細
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FTBMT 1358575-02-6 Endocrinology/Hormones GPCR/G Protein GPR inhibit Inhibitor inhibitor