Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
20 mg | 在庫あり | ¥ 18,500 | |||
100 mg | 在庫あり | ¥ 44,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 10,500 |
説明 | Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells. |
ターゲット&IC50 | α1β1γ2 GABAA receptor:17.23 μM(EC50), α1β2 GABAA receptor:9.63 μM(EC50), α1β3γ2 GABAA receptor:6.83 μM(EC50), α1β2γ2 GABAA receptor:6.3 μM(EC50) |
植物由来 |
別名 | Q-100692, KB-289522, LS-176045 |
分子量 | 324.37 |
分子式 | C20H20O4 |
CAS No. | 59870-68-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 58 mg/mL(178.8 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Glabridin 59870-68-7 DNA Damage/DNA Repair Immunology/Inflammation Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb Proteases/Proteasome Reactive Oxygen Species Tyrosinase GABA Receptor Antibacterial PPAR LS 176045 KB289522 Peroxisome proliferator-activated receptors Q 100692 Bacterial inhibit KB 289522 Q100692 Q-100692 KB-289522 LS-176045 LS176045 Inhibitor inhibitor