Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Golgicide A is a potent and rapidly reversible GBF1 inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 48,000 | |||
50 mg | 在庫あり | ¥ 91,500 | |||
100 mg | 在庫あり | ¥ 137,000 | |||
500 mg | 在庫あり | ¥ 303,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,500 |
説明 | Golgicide A is a potent and rapidly reversible GBF1 inhibitor. |
In vitro | Golgicide A inhibits the effect of shiga toxin on protein synthesis with an IC50 of 3.3 μM. Golgicide A causes a decrease in GBF1-mediated Arf1 activation, arrests secretion of soluble and membrane-anchored proteins and then impairs retrograde toxin transport. [1] Golgicide A decreases HCV RNA levels in FLRP1 cells and J6/JFH1 cells. In addition, Golgicide A causes redistribution of NS5A and accumulation of infectious viral particles in J6/JFH1 cells. [2] |
分子量 | 284.3 |
分子式 | C17H14F2N2 |
CAS No. | 1139889-93-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 14.2 mg/mL (50 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Golgicide A 1139889-93-2 Microbiology/Virology Others Virus Protease Enterovirus Rhinovirus HEVs HRVs HEV GCA inhibit Inhibitor HRV inhibitor