Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.
説明 | HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9. |
別名 | HBF 0259 |
分子量 | 364.2 |
分子式 | C16H12Cl2FN5 |
CAS No. | 957011-15-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 98 mg/mL (269.08 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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HBF-0259 957011-15-3 Immunology/Inflammation Antiviral HBsAg antigen HBV virus hepatitis HBF0259 inhibit secretion Hepatitis B virus HBF 0259 surface Inhibitor inhibitor