Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 7,000 | |||
5 mg | 在庫あり | ¥ 14,500 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 45,500 | |||
50 mg | 在庫あり | ¥ 75,500 | |||
100 mg | 在庫あり | ¥ 121,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,500 |
説明 | HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH . |
ターゲット&IC50 | TRPV4 (human):8 ± 6 nM, TRPV4 (rat):133 ± 25 nM, TRPV4 (mouse):17 ± 3 nM |
In vivo | HC-067047 caused a significant reduction of the maximal micturition pressure in rats, which might be caused by an effect on TRPV4 in smooth muscle. |
別名 | HC067047 |
分子量 | 471.51 |
分子式 | C26H28F3N3O2 |
CAS No. | 883031-03-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (53.02 mM)
You can also refer to dose conversion for different animals. 詳細
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HC-067047 883031-03-6 Membrane transporter/Ion channel TRP/TRPV Channel Transient receptor potential channels Inhibitor HC 067047 HC067047 TRP Channel inhibit inhibitor