Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HS38 is a specific and ATP-competitive DAPK inhibitor with Kds of 300 nM, 200 nM, and 280 nM for DAPK1, PIM3, and ZIPK. HS38 can be used in studies about smooth muscle-related disorders.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 15,500 | |||
25 mg | 在庫あり | ¥ 32,000 | |||
50 mg | 在庫あり | ¥ 51,000 | |||
100 mg | 在庫あり | ¥ 83,000 | |||
200 mg | 在庫あり | ¥ 123,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,000 |
説明 | HS38 is a specific and ATP-competitive DAPK inhibitor with Kds of 300 nM, 200 nM, and 280 nM for DAPK1, PIM3, and ZIPK. HS38 can be used in studies about smooth muscle-related disorders. |
ターゲット&IC50 | DAPK2:79 nM (Kd), ZIPK:280 nM (Kd), Pim3:200 nM (Kd), DAPK1:300 nM (Kd), DAPK1:IC50 : 200 nM |
In vitro | HS38 shows a Kd of 79 nM for DAPK2. In human aortic SM cells, HS38 reduces relative RLC20 phosphorylation in both the basal and S1P-activated states. In Ca2+-sensitized rabbit ileum, HS38 reduces the contractile force, MYPT1 phosphorylation, and RLC20 phosphorylation[1]. |
別名 | HS 38, HS-38 |
分子量 | 349.8 |
分子式 | C14H12ClN5O2S |
CAS No. | 1030203-81-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.4 mg/mL (18.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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HS38 1030203-81-6 Apoptosis DAPK HS 38 HS-38 Inhibitor inhibitor inhibit