store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 34,000 | |||
2 mg | 在庫あり | ¥ 45,500 | |||
5 mg | 在庫あり | ¥ 68,500 | |||
10 mg | 在庫あり | ¥ 113,500 | |||
25 mg | 在庫あり | ¥ 201,500 | |||
50 mg | 在庫あり | ¥ 271,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 75,000 |
説明 | IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual. |
ターゲット&IC50 | NMT2 (human):<1 nM, NMT1 (human):<1 nM |
In vitro | IMP-1088 (1-1000 nM) blocks production of infectious virus and inhibits single cycle replication in primary human bronchial epithelial cells (hBEC) infected with rhinovirus RV-A1 (MOI 5) for 7 h. IMP-1088 significantly inhibits production of infectious virus even when added up to 3 hours post-infection[1].IMP-1088 (500 nM) inhibits production of infectious rhinovirus particles by blocking virus assembly in HeLa cells infected with rhinovirus RV-A16 (MOI 20) for 6 h[1]. |
分子量 | 453.53 |
分子式 | C25H29F2N5O |
CAS No. | 2059148-82-0 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (209.47 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
IMP-1088 2059148-82-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Others DNA/RNA Synthesis Inhibitor NMT1 virus-encoded HsNMT2 human N-myristoyltransferases replication HeLa protein IMP1088 HsNMT1 VP0 NMT2 inhibit hBEC rhinovirus epithelial bronchial IMP 1088 RV-A16 inhibitor