Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.
説明 | JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels. |
ターゲット&IC50 | P2X7:9.1(pKi, rat), P2X7:7.9(pKi, human) |
分子量 | 446.63 |
分子式 | C28H38N4O |
CAS No. | 1428327-35-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (201.5 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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JNJ-42253432 1428327-35-8 Membrane transporter/Ion channel Neuroscience P2X Receptor JNJ 42253432 JNJ42253432 Inhibitor inhibitor inhibit