Powder: -20°C for 3 years | In solvent: -80°C for 1 year
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).
説明 | L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM). |
In vitro | L-2,4-Diaminobutyric acid(DABA) was a non-linear, non-competitive inhibitor of GABA transaminase activity. The DABA-induced elevation of GABA levels paralleled the inhibition of GABA transaminase activity. DABA was a more effective inhibitor of GABA transaminase in vivo than in vitro, and this inhibition probably produced the elevation of GABA levels. The neurotoxicity of DABA appears to produce a use in GABA replacement therapy[1]. |
別名 | L-2,4-Diaminobutyric acid, L-DAB HBR |
分子量 | 118.13 |
分子式 | C4H10N2O2 |
CAS No. | 1758-80-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
H2O: Insoluble
You can also refer to dose conversion for different animals. 詳細
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L-DABA 1758-80-1 Membrane transporter/Ion channel Metabolism Neuroscience Endogenous Metabolite GABA Receptor L-2,4-Diaminobutyric acid Gamma-aminobutyric acid Receptor Inhibitor inhibit LDABA L DABA γ-Aminobutyric acid Receptor L-DAB HBR inhibitor