Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lenalidomide-OH is a ligand of cereblon (CRBN), serving as an analog to Lenalidomide for E3 ubiquitin ligase. It is utilized in the recruitment of CRBN protein. Additionally, Lenalidomide-OH can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. An example of a PROTAC BTK degrader incorporating Lenalidomide-OH is SJF620.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 10,000 | |||
25 mg | 在庫あり | ¥ 16,000 | |||
50 mg | 在庫あり | ¥ 22,500 | |||
100 mg | 在庫あり | ¥ 34,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 37,500 |
説明 | Lenalidomide-OH is a ligand of cereblon (CRBN), serving as an analog to Lenalidomide for E3 ubiquitin ligase. It is utilized in the recruitment of CRBN protein. Additionally, Lenalidomide-OH can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. An example of a PROTAC BTK degrader incorporating Lenalidomide-OH is SJF620. |
In vitro | Lenalidomide-OH can be connected to the ligand for protein by a linker to form PROTACs which are the inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1]. |
分子量 | 260.25 |
分子式 | C13H12N2O4 |
CAS No. | 1416990-08-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (42.27 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Lenalidomide-OH 1416990-08-3 PROTAC Ligand for E3 Ligase LenalidomideOH inhibit E3 ligase-recruiting Moiety Inhibitor Ligands for E3 Ligase Lenalidomide OH inhibitor