Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
In vitro | Litronesib (LY2523355) functions as a selective inhibitor of Eg5, promoting cancer cell death by inducing mitotic arrest at a concentration of 25 nM. This process requires the prolonged activation of the spindle-assembly checkpoint (SAC)[1]. |
別名 | KF-89617, LY-2523355 |
分子量 | 511.7 |
分子式 | C23H37N5O4S2 |
CAS No. | 910634-41-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (97.71 mM)
You can also refer to dose conversion for different animals. 詳細
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Litronesib 910634-41-2 Cytoskeletal Signaling Kinesin KF-89617 KF89617 LY-2523355 LY 2523355 LY2523355 KF 89617 Inhibitor inhibitor inhibit