keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 112,000 | |||
10 mg | 在庫あり | ¥ 160,000 | |||
25 mg | 在庫あり | ¥ 250,500 | |||
50 mg | 在庫あり | ¥ 342,000 | |||
100 mg | 在庫あり | ¥ 454,500 |
説明 | M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM. |
分子量 | 2041.38 |
分子式 | C96H149N23O26 |
CAS No. | TP1992L |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
M40 acetate(143896-17-7 free base) TP1992L GPCR/G Protein Neuroscience Neuropeptide Y Receptor M-40 acetate(143896-17-7 free base) M40 acetate(143896 17 7 free base) M40 acetate(143896177 free base) Inhibitor inhibitor inhibit