Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.
説明 | MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5. |
ターゲット&IC50 | PDE1:>100 μM (IC50), PDE3:>100 μM (IC50), PDE2:>100 μM (IC50), PDE5:19 nM (IC50), PDE4:>100 μM (IC50) |
In vitro | MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins[1]. |
分子量 | 313.74 |
分子式 | C16H12ClN3O2 |
CAS No. | 150450-53-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (79.68 mM)
You can also refer to dose conversion for different animals. 詳細
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MBCQ 150450-53-6 Metabolism PDE cGMP-PDE inhibit arteries PGF2α Inhibitor Phosphodiesterase (PDE) coronary inhibitor