Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MRZ 2-514 (8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one) is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 80,000 |
5 mg | 在庫あり | ¥ 169,500 |
10 mg | 在庫あり | ¥ 228,500 |
25 mg | 在庫あり | ¥ 374,000 |
50 mg | 在庫あり | ¥ 503,000 |
100 mg | 在庫あり | ¥ 684,000 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 157,500 |
説明 | MRZ 2-514 (8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one) is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM. |
ターゲット&IC50 | AMPA:72.7 μM, NMDA:33 μM (Ki) |
In vitro | MRZ 2-514 against peak AMPA-induced currents with IC50 values of 72.7 μM[1]. |
In vivo | In mice, MRZ 2-514 has anticonvulsive action in the MES model, and the effect is prolonged by probenecid[1]. |
別名 | 8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one |
分子量 | 308.09 |
分子式 | C11H6BrN3O3 |
CAS No. | 202808-11-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.33 mg/ml (59.51 mM)
You can also refer to dose conversion for different animals. 詳細
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MRZ 2-514 202808-11-5 Neuroscience NMDAR inhibit Inhibitor MRZ 2514 MRZ 2 514 iGluR Ionotropic glutamate receptors 8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one inhibitor