Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Glycolylneuraminic acid (GcNeu) is a nonhuman sialic acid molecule synthesized in pigs. N-Glycolylneuraminic acid is a receptor of human and animal IAVs.
説明 | N-Glycolylneuraminic acid (GcNeu) is a nonhuman sialic acid molecule synthesized in pigs. N-Glycolylneuraminic acid is a receptor of human and animal IAVs. |
In vitro | Expression of N-Glycolylneuraminic acid on human cells clearly suppressed infectivity of IAVs that possess N-Glycolylneuraminic acid binding ability. Furthermore, there was no difference in infectivity of a transfectant virus that included the wild-type HA gene from A/Memphis/1/1971 (H3N2), which shows no N-Glycolylneuraminic acid binding, between parent MCF7 cells and cells stably expressing the monkey CMAH gene (CMAH-MCF7 cells). On the other hand, cell entry of the transfectant virus that included the N-Glycolylneuraminic acid-binding HA gene with a single mutation to Tyr at position Thr155 was arrested at the stage of internalization from the plasma membrane of the CMAH-MCF7 cells[1]. |
別名 | NeuGc, GcNeu |
分子量 | 325.27 |
分子式 | C11H19NO10 |
CAS No. | 1113-83-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 76 mg/mL (233.65 mM)
You can also refer to dose conversion for different animals. 詳細
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N-Glycolylneuraminic acid 1113-83-3 Metabolism Microbiology/Virology Influenza Virus Endogenous Metabolite NeuGc Inhibitor NGlycolylneuraminic acid inhibit N Glycolylneuraminic acid GcNeu inhibitor