Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cathepsin E, and cathepsin D.
ターゲット&IC50 | BACE1 (mouse , human):5 nM , BACE2:6 nM |
分子量 | 449.4 |
分子式 | C21H19F4N5O2 |
CAS No. | 1262857-73-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (100.13 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
NB-360 1262857-73-7 Neuroscience BACE Inhibitor β-Secretase inhibit NB360 Beta-secretase NB 360 inhibitor