Powder: -20°C for 3 years | In solvent: -80°C for 1 year
8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 36,000 |
5 mg | 在庫あり | ¥ 76,500 |
10 mg | 在庫あり | ¥ 130,500 |
25 mg | 在庫あり | ¥ 206,000 |
50 mg | お問い合わせ | ¥ 271,000 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 85,500 |
説明 | 8-Geranyloxypsoralen inhibits α2-secretase (BACE1) activity in non-competitive manner, with the IC(50) values <25.0 μM, it can induce vasorelaxation on rat arterial tissues. 8-Geranyloxypsoralen possesses nematicidal activities, the median lethal concentrations (LC(50)) is 188.3 mg/ L against B. xylophilus and is 117.5 mg/L against P. redivivus. |
ターゲット&IC50 | CYP3A4:3.93 μM (IC50) |
In vitro | Through bioassay-guided fractionations, three coumarins were obtained from the extract of H. candicans and determined to be 8-Geranyloxypsoralen (1), imperatorin (2), and heraclenin (3) based on spectra data. All three compounds possessed nematicidal activities against the two tested nematodes. The median lethal concentrations (LC(50)) of compounds 1-3 at 72 h were 188.3, 161.7, and 114.7 mg L(-1) respectively against B. xylophilus and were 117.5, 179.0, and 148.7 mg L(-1) respectively against P. redivivus[1] |
植物由来 |
分子量 | 338.4 |
分子式 | C21H22O4 |
CAS No. | 7437-55-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (132.98 mM)
You can also refer to dose conversion for different animals. 詳細
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8-Geranyloxypsoralen 7437-55-0 Metabolism Microbiology/Virology Neuroscience BACE P450 Anti-infection CYPs Cytochrome P450 8Geranyloxypsoralen inhibit Inhibitor 8 Geranyloxypsoralen inhibitor