Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respectively).
説明 | NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respectively). |
ターゲット&IC50 | AC type III:132 μM, AC type V:8.3 μM, AC type II:1.7 mM |
In vitro | NKY80 (20 μM) blocks the increase in LVP and ventricular cAMP levels[2]. NKY80 (20 μM; 2 hours) completely blocks the elevations in both cAMP content and renin release from isolated JG cells[3]. |
別名 | Adenylyl cyclase type V Inhibitor |
分子量 | 229.23 |
分子式 | C12H11N3O2 |
CAS No. | 299442-43-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 225 mg/mL (981.5 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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NKY80 299442-43-6 Neuroscience Adenylyl cyclase Adenylyl cyclase type V Inhibitor NKY 80 NKY-80 Inhibitor inhibitor inhibit