Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 35,500 | |||
5 mg | 在庫あり | ¥ 75,500 | |||
10 mg | 在庫あり | ¥ 129,500 | |||
25 mg | 在庫あり | ¥ 204,500 | |||
50 mg | 在庫あり | ¥ 282,500 | |||
100 mg | 在庫あり | ¥ 383,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 83,500 |
説明 | Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) . |
ターゲット&IC50 | NAMPT: |
In vitro | Nampt-IN-5 shows a good ADME data: mouse microsomal clearance, CYP3A4 inhibition value (0.75 μM), Sol6.8: 0.056 mM; MDCK Papp AB: 18.6.Nampt-IN-5 has cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively in CellTiterGlo (CTG) assays[1]. |
分子量 | 427.5 |
分子式 | C25H25N5O2 |
CAS No. | 2380013-17-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 48 mg/mL (112.28 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Nampt-IN-5 2380013-17-0 Metabolism P450 NAMPT A2780 COR-L23 Nicotinamide phosphoribosyl transferase Inhibitor NamptIN5 Visfatin CYPs inhibit Pre-B cell colony enhancing factor PBEF Cytochrome P450 Nampt IN 5 inhibitor