Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor.
説明 | Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5-HT2B receptor. |
ターゲット&IC50 | A2A receptoor:(ki)220 nM, GPR68:(pEC50)6.83 , 5-HT2B receptor:(ki)736 nM |
分子量 | 307.35 |
分子式 | C17H17N5O |
CAS No. | 1309198-71-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (813.40 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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