Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties.
説明 | Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties. |
ターゲット&IC50 | Macrophages:57.4 mM(EC50), PBMC:22.7 mM (EC50), Monocyte:24.6 mM (EC50) |
キナーゼ試験 | Cerebral cortices from male Sprague-Dawley rats (200-300 g) are homogenized in 9 volumes of ice-cold 0.32mol/Lsucrose by nine strokes with a Teflon/glass homogenizer at 500 rpm. The homogenate is centrifuged for 10 min at 1×103 g, and the supernatant is recentrifuged at 1×104 g for 20 min at 4°C. The pellet is suspended in assay buffer (118 mM NaCl/4.7 mM KCl/1.2 mM MgSO4/5 mM NaHCO3/20 mM Hepes/1.2 mM KH2PO4/2.5 mM CaCl2/11 mM glucose, pH 7.4) and incubated at 23°C for 20 min prior to final centrifugation at 1×103 g for 20 min at 4°C. The pellet is resuspended in assay buffer (70 mL per gram of original tissue). Binding of [3H]MK-801 is measured by incubating 750 μL duplicate aliquots of this crude membrane suspension (=0.75 mg of protein) with 100 μL of buffer containing displacer or of buffer alone (total binding), 100 μL of 50 nM [3H]MK-801, and 50 μL of buffer for 60 min at 23°C. Nonspecific binding is defined by 100 μM (final concentration) unlabeled MK-801. |
植物由来 |
別名 | 3-Oxooleanolic acid, 3-Oxoolean-12-en-28-oic Acid, Oleanonic Acid, 3-Ketooleanolic Acid |
分子量 | 454.68 |
分子式 | C30H46O3 |
CAS No. | 17990-42-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (219.93 mM), Sonication is recommended.
H2O: < 0.1 mg/mL (insoluble)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Oleanonic acid 17990-42-0 Microbiology/Virology Proteases/Proteasome HIV Protease 3-Oxooleanolic acid 3-Oxoolean-12-en-28-oic Acid Oleanonic Acid HIV Human immunodeficiency virus inhibit Inhibitor 3-Ketooleanolic Acid inhibitor