Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)
説明 | PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM) |
In vivo | A glutaminyl cyclase (QC) inhibitor, PBD150, was shown to be able to reduce the deposition of pyroglutamate-modified amyloid-β peptides in brain of transgenic mouse models of Alzheimer disease, leading to a significant improvement of learning and memory in those transgenic animals[1]. |
分子量 | 320.41 |
分子式 | C15H20N4O2S |
CAS No. | 790663-33-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (390.13 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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PBD-150 790663-33-1 Neuroscience Beta Amyloid Inhibitor Amyloid-β Abeta β-amyloid peptide inhibit Alzheimer PBD 150 PBD150 inhibitor